EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection

Schizophrenia is a chronic and severe mental illness that significantly impacts the daily lives and work of those affected. Unfortunately, schizophrenia with negative symptoms often gets misdiagnosed, relying heavily on the clinician’s experience. There is a pressing need to develop an objective and...

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Main Authors: Alanoud Al Mazroa, Majdy M. Eltahir, Shouki A. Ebad, Faiz Abdullah Alotaibi, Venkatachalam K, Jaehyuk Cho
Format: Article
Language:English
Published: PeerJ Inc. 2025-05-01
Series:PeerJ Computer Science
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Online Access:https://peerj.com/articles/cs-2811.pdf
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author Alanoud Al Mazroa
Majdy M. Eltahir
Shouki A. Ebad
Faiz Abdullah Alotaibi
Venkatachalam K
Jaehyuk Cho
author_facet Alanoud Al Mazroa
Majdy M. Eltahir
Shouki A. Ebad
Faiz Abdullah Alotaibi
Venkatachalam K
Jaehyuk Cho
author_sort Alanoud Al Mazroa
collection DOAJ
description Schizophrenia is a chronic and severe mental illness that significantly impacts the daily lives and work of those affected. Unfortunately, schizophrenia with negative symptoms often gets misdiagnosed, relying heavily on the clinician’s experience. There is a pressing need to develop an objective and effective diagnostic method for this specific type of schizophrenia. This paper proposes a new deep-learning method called Cascaded Atrous Convolutional Network with Adaptive Weight Fusion (CA-AWFM) for classifying schizophrenia from electroencephalogram (EEG) data that combines cascaded networks with atrous convolutions and an adaptive weight fusion module (AWFM). This is because schizophrenia involves intricate and subtle brain wave patterns that make it difficult to detect the disorder from EEG signals. As such, our model uses an “atrous” convolution operation to extract multi-scale temporal information and a cascade network structure that progressively improves the attribute representations across layers. For classification purposes, AWFM enables our model to modify the importance of features dynamically. We evaluated our technique using a publicly available dataset of EEG recordings acquired from patients who have schizophrenia and everyday individuals. The proposed model has significantly outperformed existing methods with a 99.5% accuracy rate. With the help of atrous convolutions, local and global dependencies within the EEGs can be effectively modeled in this way. At the same time, AWFM makes flexible prioritization of characteristics possible for improved classification performance. With such impressive figures achieved, it can be concluded that our approach should be considered as accurate enough for routine clinical use in identifying schizophrenic patients early on so they can receive intervention measures on time or when diagnosed late, then dealt with appropriately.
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spelling doaj-art-62efeda5be2d40919ed5c655ff346e4e2025-08-20T02:58:55ZengPeerJ Inc.PeerJ Computer Science2376-59922025-05-0111e281110.7717/peerj-cs.2811EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selectionAlanoud Al Mazroa0Majdy M. Eltahir1Shouki A. Ebad2Faiz Abdullah Alotaibi3Venkatachalam K4Jaehyuk Cho5Department of Information Systems, Princess Nourah bint Abdulrahman University, Riyadh, Saudi ArabiaDepartment of Information Systems, King Khalid University, Abha, Saudi ArabiaCenter for Scientific Research and Entrepreneurship, Northern Border University, Arar, Saudi ArabiaDepartment of Information Science, King Saud University, Riyadh, Saudi ArabiaDepartment of Software Engineering, Jeonbuk National University, Jeonju, Republic of KoreaDepartment of Software Engineering and Division of Electronics & Information Engineering, Jeonbuk National University, Jeonju, Republic of KoreaSchizophrenia is a chronic and severe mental illness that significantly impacts the daily lives and work of those affected. Unfortunately, schizophrenia with negative symptoms often gets misdiagnosed, relying heavily on the clinician’s experience. There is a pressing need to develop an objective and effective diagnostic method for this specific type of schizophrenia. This paper proposes a new deep-learning method called Cascaded Atrous Convolutional Network with Adaptive Weight Fusion (CA-AWFM) for classifying schizophrenia from electroencephalogram (EEG) data that combines cascaded networks with atrous convolutions and an adaptive weight fusion module (AWFM). This is because schizophrenia involves intricate and subtle brain wave patterns that make it difficult to detect the disorder from EEG signals. As such, our model uses an “atrous” convolution operation to extract multi-scale temporal information and a cascade network structure that progressively improves the attribute representations across layers. For classification purposes, AWFM enables our model to modify the importance of features dynamically. We evaluated our technique using a publicly available dataset of EEG recordings acquired from patients who have schizophrenia and everyday individuals. The proposed model has significantly outperformed existing methods with a 99.5% accuracy rate. With the help of atrous convolutions, local and global dependencies within the EEGs can be effectively modeled in this way. At the same time, AWFM makes flexible prioritization of characteristics possible for improved classification performance. With such impressive figures achieved, it can be concluded that our approach should be considered as accurate enough for routine clinical use in identifying schizophrenic patients early on so they can receive intervention measures on time or when diagnosed late, then dealt with appropriately.https://peerj.com/articles/cs-2811.pdfSchizophrenia detectionEEGDeep learningAtrous convolutionAdaptive weight fusion moduleMental health diagnosis
spellingShingle Alanoud Al Mazroa
Majdy M. Eltahir
Shouki A. Ebad
Faiz Abdullah Alotaibi
Venkatachalam K
Jaehyuk Cho
EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
PeerJ Computer Science
Schizophrenia detection
EEG
Deep learning
Atrous convolution
Adaptive weight fusion module
Mental health diagnosis
title EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
title_full EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
title_fullStr EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
title_full_unstemmed EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
title_short EEG-based schizophrenia diagnosis using deep learning with multi-scale and adaptive feature selection
title_sort eeg based schizophrenia diagnosis using deep learning with multi scale and adaptive feature selection
topic Schizophrenia detection
EEG
Deep learning
Atrous convolution
Adaptive weight fusion module
Mental health diagnosis
url https://peerj.com/articles/cs-2811.pdf
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