Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms

Conclusion: This study revealed the importance of granulocyte subsets and Ifitm1 in SCI, proposed Ifitm1 as a potential therapeutic target, and provided new insights into the molecular mechanisms of SCI.

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Main Authors: Yu Yao, Kun Xi, Shaohu Xu, Feiyu Zhang, Liang Chen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/mi/6149780
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author Yu Yao
Kun Xi
Shaohu Xu
Feiyu Zhang
Liang Chen
author_facet Yu Yao
Kun Xi
Shaohu Xu
Feiyu Zhang
Liang Chen
author_sort Yu Yao
collection DOAJ
description Conclusion: This study revealed the importance of granulocyte subsets and Ifitm1 in SCI, proposed Ifitm1 as a potential therapeutic target, and provided new insights into the molecular mechanisms of SCI.
format Article
id doaj-art-62edaecbdce7498084c758c6b239ead6
institution Kabale University
issn 1466-1861
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Mediators of Inflammation
spelling doaj-art-62edaecbdce7498084c758c6b239ead62025-08-20T04:03:22ZengWileyMediators of Inflammation1466-18612025-01-01202510.1155/mi/6149780Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning AlgorithmsYu Yao0Kun Xi1Shaohu Xu2Feiyu Zhang3Liang Chen4Department of OrthopedicsDepartment of OrthopedicsDepartment of Spine SurgeryDepartment of Spine SurgeryDepartment of OrthopedicsConclusion: This study revealed the importance of granulocyte subsets and Ifitm1 in SCI, proposed Ifitm1 as a potential therapeutic target, and provided new insights into the molecular mechanisms of SCI.http://dx.doi.org/10.1155/mi/6149780
spellingShingle Yu Yao
Kun Xi
Shaohu Xu
Feiyu Zhang
Liang Chen
Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
Mediators of Inflammation
title Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
title_full Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
title_fullStr Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
title_full_unstemmed Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
title_short Identification of Ifitm1 as a Pivotal Gene in Mouse Spinal Cord Injury Using Comprehensive Machine Learning Algorithms
title_sort identification of ifitm1 as a pivotal gene in mouse spinal cord injury using comprehensive machine learning algorithms
url http://dx.doi.org/10.1155/mi/6149780
work_keys_str_mv AT yuyao identificationofifitm1asapivotalgeneinmousespinalcordinjuryusingcomprehensivemachinelearningalgorithms
AT kunxi identificationofifitm1asapivotalgeneinmousespinalcordinjuryusingcomprehensivemachinelearningalgorithms
AT shaohuxu identificationofifitm1asapivotalgeneinmousespinalcordinjuryusingcomprehensivemachinelearningalgorithms
AT feiyuzhang identificationofifitm1asapivotalgeneinmousespinalcordinjuryusingcomprehensivemachinelearningalgorithms
AT liangchen identificationofifitm1asapivotalgeneinmousespinalcordinjuryusingcomprehensivemachinelearningalgorithms