Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep

In this paper, a model for the transmission dynamics of cystic echinococcosis in the dog, sheep, and human populations is developed and analyzed. We first model and analyze the predator-prey interaction model in these populations; then, we propose a mathematical model of the transmission dynamics of...

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Main Authors: Getachew Bitew Birhan, Justin Manango W. Munganga, Adamu Shitu Hassan
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Applied Mathematics
Online Access:http://dx.doi.org/10.1155/2020/8482696
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author Getachew Bitew Birhan
Justin Manango W. Munganga
Adamu Shitu Hassan
author_facet Getachew Bitew Birhan
Justin Manango W. Munganga
Adamu Shitu Hassan
author_sort Getachew Bitew Birhan
collection DOAJ
description In this paper, a model for the transmission dynamics of cystic echinococcosis in the dog, sheep, and human populations is developed and analyzed. We first model and analyze the predator-prey interaction model in these populations; then, we propose a mathematical model of the transmission dynamics of cystic echinococcosis. We calculate the basic reproduction number R0 and prove that the disease-free equilibrium is globally asymptotically stable, and hence, the disease dies out if R0<1. We further show that the endemic equilibrium is globally asymptotically stable, and hence, the disease persists if R0>1. Numerical simulations are performed to illustrate our analytic results. We give sensitivity analysis of the key parameters and give strategies that are helpful to control the transmission of cystic echinococcosis, from which the most sensitive parameter is the transmission rate of Echinococcus’ eggs from the environment to sheep (βes). Thus, the effective controlling strategies are associated with this parameter.
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institution Kabale University
issn 1110-757X
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language English
publishDate 2020-01-01
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series Journal of Applied Mathematics
spelling doaj-art-62e999010c024d9999a2f345b0c54a2d2025-08-20T03:34:40ZengWileyJournal of Applied Mathematics1110-757X1687-00422020-01-01202010.1155/2020/84826968482696Mathematical Modeling of Echinococcosis in Humans, Dogs, and SheepGetachew Bitew Birhan0Justin Manango W. Munganga1Adamu Shitu Hassan2Department of Mathematical Sciences, College of Science, Engineering and Technology, University of South Africa, South AfricaDepartment of Mathematical Sciences, College of Science, Engineering and Technology, University of South Africa, South AfricaDepartment of Mathematical Sciences, College of Science, Engineering and Technology, University of South Africa, South AfricaIn this paper, a model for the transmission dynamics of cystic echinococcosis in the dog, sheep, and human populations is developed and analyzed. We first model and analyze the predator-prey interaction model in these populations; then, we propose a mathematical model of the transmission dynamics of cystic echinococcosis. We calculate the basic reproduction number R0 and prove that the disease-free equilibrium is globally asymptotically stable, and hence, the disease dies out if R0<1. We further show that the endemic equilibrium is globally asymptotically stable, and hence, the disease persists if R0>1. Numerical simulations are performed to illustrate our analytic results. We give sensitivity analysis of the key parameters and give strategies that are helpful to control the transmission of cystic echinococcosis, from which the most sensitive parameter is the transmission rate of Echinococcus’ eggs from the environment to sheep (βes). Thus, the effective controlling strategies are associated with this parameter.http://dx.doi.org/10.1155/2020/8482696
spellingShingle Getachew Bitew Birhan
Justin Manango W. Munganga
Adamu Shitu Hassan
Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
Journal of Applied Mathematics
title Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
title_full Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
title_fullStr Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
title_full_unstemmed Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
title_short Mathematical Modeling of Echinococcosis in Humans, Dogs, and Sheep
title_sort mathematical modeling of echinococcosis in humans dogs and sheep
url http://dx.doi.org/10.1155/2020/8482696
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