Physicochemical quality assessment of four asparaginases.
L-Asparaginases (ASNases) are used for the treatment of acute lymphoblastic leukaemia. There are reports of quality problems for some therapeutic asparaginase products, especially those manufactured in middle-income countries. These products may exhibit decreased potency and/or decreased specific ac...
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| Main Authors: | Vanessa Radtke, Thorsten König, Christoph Radcke, Ulf Bergmann, Rene Eichler, Katja J Pohl, Arndt Schnuchel |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0326106 |
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