EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS
Sildenafil citrate (Viagra) is an oral medication used to treat male impotence by the inhibition of phosphodiesterase-5 in the corpus cavernosum and subsequent facilitation of penile erection. The side effects of sildenafil citrate have been reported. The present study was designed to investigate th...
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| Format: | Article |
| Language: | English |
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College of Veterinary Medicine, University of Basrah, Iraq
2009-12-01
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| Series: | Basrah Journal of Veterinary Research |
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| Online Access: | https://bjvr.uobasrah.edu.iq/article_56909_0f298ea9c176d97fb5871b0a3a2f572c.pdf |
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| _version_ | 1849321509342937088 |
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| author | Khalid G. Al-Fartosi |
| author_facet | Khalid G. Al-Fartosi |
| author_sort | Khalid G. Al-Fartosi |
| collection | DOAJ |
| description | Sildenafil citrate (Viagra) is an oral medication used to treat male impotence by the inhibition of phosphodiesterase-5 in the corpus cavernosum and subsequent facilitation of penile erection. The side effects of sildenafil citrate have been reported. The present study was designed to investigate the effect of long term administration of sildenafil citrate on some characteristics (sperm count, sperm malformations) and testis architecture of male rats. The results indicated that the oral administration of 50 mg and 100 mg of suldinafil citrate (Viagra) for 8 weeks caused a significant decreased and a significant increased in sperm count and sperm malformations respectively. The results were showed the histopathological changes in testis of male rats treated with 50 mg and 100 mg sildenafil citrate.. |
| format | Article |
| id | doaj-art-62ce66f09c074e2382186e911f43ef08 |
| institution | Kabale University |
| issn | 1813-8497 2410-8456 |
| language | English |
| publishDate | 2009-12-01 |
| publisher | College of Veterinary Medicine, University of Basrah, Iraq |
| record_format | Article |
| series | Basrah Journal of Veterinary Research |
| spelling | doaj-art-62ce66f09c074e2382186e911f43ef082025-08-20T03:49:45ZengCollege of Veterinary Medicine, University of Basrah, IraqBasrah Journal of Veterinary Research1813-84972410-84562009-12-01829110310.33762/bvetr.2009.5690956909EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATSKhalid G. Al-FartosiSildenafil citrate (Viagra) is an oral medication used to treat male impotence by the inhibition of phosphodiesterase-5 in the corpus cavernosum and subsequent facilitation of penile erection. The side effects of sildenafil citrate have been reported. The present study was designed to investigate the effect of long term administration of sildenafil citrate on some characteristics (sperm count, sperm malformations) and testis architecture of male rats. The results indicated that the oral administration of 50 mg and 100 mg of suldinafil citrate (Viagra) for 8 weeks caused a significant decreased and a significant increased in sperm count and sperm malformations respectively. The results were showed the histopathological changes in testis of male rats treated with 50 mg and 100 mg sildenafil citrate..https://bjvr.uobasrah.edu.iq/article_56909_0f298ea9c176d97fb5871b0a3a2f572c.pdfsildenafilsperm characteristicstestis architecture |
| spellingShingle | Khalid G. Al-Fartosi EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS Basrah Journal of Veterinary Research sildenafil sperm characteristics testis architecture |
| title | EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS |
| title_full | EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS |
| title_fullStr | EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS |
| title_full_unstemmed | EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS |
| title_short | EFFECT OF LONG-TERM ADMINISTRATION OF SILDENAFIL CITRATE (VIAGRA) ON SOME SPERM CHARACTERISTICS AND TESTIS ARCHITECTURE OF MALE RATS |
| title_sort | effect of long term administration of sildenafil citrate viagra on some sperm characteristics and testis architecture of male rats |
| topic | sildenafil sperm characteristics testis architecture |
| url | https://bjvr.uobasrah.edu.iq/article_56909_0f298ea9c176d97fb5871b0a3a2f572c.pdf |
| work_keys_str_mv | AT khalidgalfartosi effectoflongtermadministrationofsildenafilcitrateviagraonsomespermcharacteristicsandtestisarchitectureofmalerats |