A systematic review on the correlation between COVID-19 and lower urinary tract symptoms
COVID-19 can lead to extrapulmonary symptoms such as Lower Urinary Tract Symptoms (LUTS). We aimed to investigate the impact of the severity of SARS-CoV-2 infection on the lower urinary tract in patients affected by COVID-19. We conducted a comprehensive literature search using the terms ''...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-02-01
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| Series: | Journal of Clinical Virology Plus |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2667038025000018 |
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| author | Ashkan Shafigh Amir Mohammadi-Garebagh Kavous Shahsavarinia Sona Tayebi Ali Mostafaei Hanieh Salehi-Pourmehr Sakineh Hajebrahimi |
| author_facet | Ashkan Shafigh Amir Mohammadi-Garebagh Kavous Shahsavarinia Sona Tayebi Ali Mostafaei Hanieh Salehi-Pourmehr Sakineh Hajebrahimi |
| author_sort | Ashkan Shafigh |
| collection | DOAJ |
| description | COVID-19 can lead to extrapulmonary symptoms such as Lower Urinary Tract Symptoms (LUTS). We aimed to investigate the impact of the severity of SARS-CoV-2 infection on the lower urinary tract in patients affected by COVID-19. We conducted a comprehensive literature search using the terms ''COVID-19,'' ''SARS-CoV-2,'' and ''Lower Urinary Tract Symptoms'' with various combinations in MEDLINE, Scopus, ProQuest, Web of Science, Google Scholar, and Cochrane Library, including Cochrane Central Register of Controlled Trials (CENTRAL) and Cochrane Database of Systematic Reviews (CDSR) databases. The studies were selected based on eligibility criteria, and quantitative data were extracted using the data extraction tool from JBI-MAStARI. A total of 988 articles were found through the literature search. Twenty-five articles were included in our qualitative evaluation, and seven studies were included in the quantitative analysis. The qualitative publications were systematically reviewed separately under the titles of LUTS, benign prostatic hyperplasia (BPH), and kidney failures or kidney transplant recipients. The analysis of eligible studies showed a 3.3 % prevalence of LUTS in infected patients (95 % CI: 2.0 % - 5.3 %; Q-value: 1021.397, I2: 97.45 %). Furthermore, frequency and urgency were the most prevalent symptoms in the eligible meta-analysis studies, with 15.3 % (95 % CI: 5.7 % – 34.9 % in 4 studies) and 11.5 % (95 % CI: 7.1 % - 18.1 % in two studies), respectively. The prevalence of LUTS among COVID-19 patients was 3.3 %, with common symptoms including urinary frequency, urgency, UTI, and hematuria. Long-term follow-up and consideration of pre-existing LUTS are essential for improving understanding and clinical management. |
| format | Article |
| id | doaj-art-62cc28b0338b4c6d9caf63a876838763 |
| institution | Kabale University |
| issn | 2667-0380 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Clinical Virology Plus |
| spelling | doaj-art-62cc28b0338b4c6d9caf63a8768387632025-02-08T05:01:32ZengElsevierJournal of Clinical Virology Plus2667-03802025-02-0151100202A systematic review on the correlation between COVID-19 and lower urinary tract symptomsAshkan Shafigh0Amir Mohammadi-Garebagh1Kavous Shahsavarinia2Sona Tayebi3Ali Mostafaei4Hanieh Salehi-Pourmehr5Sakineh Hajebrahimi6Research Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranStudent Research Committee, Tabriz University of Medical Sciences, Tabriz, IranResearch Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranUrology Department, School of Medicine, Iran University of Medical Sciences, Tehran, IranResearch Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, IranResearch Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding authors at: Research Center for Evidence-based Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Azadi Street- Golgasht Ave, Tabriz, 5166/15731 East Azarbaijan, Iran.Research Center for Evidence-Based Medicine, Iranian EBM Centre: A JBI Centre of Excellence, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran; Corresponding authors at: Research Center for Evidence-based Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Azadi Street- Golgasht Ave, Tabriz, 5166/15731 East Azarbaijan, Iran.COVID-19 can lead to extrapulmonary symptoms such as Lower Urinary Tract Symptoms (LUTS). We aimed to investigate the impact of the severity of SARS-CoV-2 infection on the lower urinary tract in patients affected by COVID-19. We conducted a comprehensive literature search using the terms ''COVID-19,'' ''SARS-CoV-2,'' and ''Lower Urinary Tract Symptoms'' with various combinations in MEDLINE, Scopus, ProQuest, Web of Science, Google Scholar, and Cochrane Library, including Cochrane Central Register of Controlled Trials (CENTRAL) and Cochrane Database of Systematic Reviews (CDSR) databases. The studies were selected based on eligibility criteria, and quantitative data were extracted using the data extraction tool from JBI-MAStARI. A total of 988 articles were found through the literature search. Twenty-five articles were included in our qualitative evaluation, and seven studies were included in the quantitative analysis. The qualitative publications were systematically reviewed separately under the titles of LUTS, benign prostatic hyperplasia (BPH), and kidney failures or kidney transplant recipients. The analysis of eligible studies showed a 3.3 % prevalence of LUTS in infected patients (95 % CI: 2.0 % - 5.3 %; Q-value: 1021.397, I2: 97.45 %). Furthermore, frequency and urgency were the most prevalent symptoms in the eligible meta-analysis studies, with 15.3 % (95 % CI: 5.7 % – 34.9 % in 4 studies) and 11.5 % (95 % CI: 7.1 % - 18.1 % in two studies), respectively. The prevalence of LUTS among COVID-19 patients was 3.3 %, with common symptoms including urinary frequency, urgency, UTI, and hematuria. Long-term follow-up and consideration of pre-existing LUTS are essential for improving understanding and clinical management.http://www.sciencedirect.com/science/article/pii/S2667038025000018COVID-19Lower urinary tract symptomsLUTSSystematic review |
| spellingShingle | Ashkan Shafigh Amir Mohammadi-Garebagh Kavous Shahsavarinia Sona Tayebi Ali Mostafaei Hanieh Salehi-Pourmehr Sakineh Hajebrahimi A systematic review on the correlation between COVID-19 and lower urinary tract symptoms Journal of Clinical Virology Plus COVID-19 Lower urinary tract symptoms LUTS Systematic review |
| title | A systematic review on the correlation between COVID-19 and lower urinary tract symptoms |
| title_full | A systematic review on the correlation between COVID-19 and lower urinary tract symptoms |
| title_fullStr | A systematic review on the correlation between COVID-19 and lower urinary tract symptoms |
| title_full_unstemmed | A systematic review on the correlation between COVID-19 and lower urinary tract symptoms |
| title_short | A systematic review on the correlation between COVID-19 and lower urinary tract symptoms |
| title_sort | systematic review on the correlation between covid 19 and lower urinary tract symptoms |
| topic | COVID-19 Lower urinary tract symptoms LUTS Systematic review |
| url | http://www.sciencedirect.com/science/article/pii/S2667038025000018 |
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