The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes
The use of tobacco products is one of the most preventable risk factors for mortality from a variety of diseases, including cardiovascular, infectious, respiratory, and neoplastic conditions. The use of electronic cigarettes (ECIGs), also known as electronic nicotine delivery devices, has increased...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-02-01
|
| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325001897 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1825206950291308544 |
|---|---|
| author | Kamila Melnikov Alžbeta Kaiglová Soňa Kucharíková |
| author_facet | Kamila Melnikov Alžbeta Kaiglová Soňa Kucharíková |
| author_sort | Kamila Melnikov |
| collection | DOAJ |
| description | The use of tobacco products is one of the most preventable risk factors for mortality from a variety of diseases, including cardiovascular, infectious, respiratory, and neoplastic conditions. The use of electronic cigarettes (ECIGs), also known as electronic nicotine delivery devices, has increased significantly in recent years. Nicotine, propylene glycol, and / or glycerine, water, alcohol, flavorings, and other substances are among the many chemicals found in ECIGs that are vaporized and inhaled. A review of the existing literature shows that research dedicated to ECIGs is a rapidly developing and growing field of study. The rationale for the use of ECIGs is that they represent a safer alternative to traditional tobacco products. However, vaping safety profiles are still under development, as this is a relatively recent phenomenon. Various model organisms can be employed to examine the cellular processes that may be altered by exposure to the electronic liquids utilized for vaping. For example, the translucent multicellular eukaryote Caenorhabditis elegans is widely used as a model organism to explain a broad range of biological processes, including aging, stress response, development, and many others. Due to its short lifespan and easy use, C. elegans is an ideal model organism for studying chronic exposure to drugs and environmental toxicology. This review presents a summary of the most recent findings on the impact of electronic cigarettes on the physiological health of this nematode. Preliminary observations made in C. elegans can provide insight into the consequences of exposure to fundamental cellular physiology, which can then be used for future research in humans and mammalian models. |
| format | Article |
| id | doaj-art-62ca498d29be4cc4bbbc490c2184f6b6 |
| institution | Kabale University |
| issn | 0147-6513 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Ecotoxicology and Environmental Safety |
| spelling | doaj-art-62ca498d29be4cc4bbbc490c2184f6b62025-02-07T04:46:37ZengElsevierEcotoxicology and Environmental Safety0147-65132025-02-01291117853The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettesKamila Melnikov0Alžbeta Kaiglová1Soňa Kucharíková2Department of Laboratory Medicine, Faculty of Health Care and Social Work, Trnava University in Trnava, Univerzitné námestie 1, Trnava 918 43, SlovakiaDepartment of Laboratory Medicine, Faculty of Health Care and Social Work, Trnava University in Trnava, Univerzitné námestie 1, Trnava 918 43, SlovakiaCorrespondence to: Trnava University in Trnava, Faculty of Health Care and Social Work, Department of Laboratory Medicine, Univerzitné námestie 1, Trnava 918 43, Slovakia.; Department of Laboratory Medicine, Faculty of Health Care and Social Work, Trnava University in Trnava, Univerzitné námestie 1, Trnava 918 43, SlovakiaThe use of tobacco products is one of the most preventable risk factors for mortality from a variety of diseases, including cardiovascular, infectious, respiratory, and neoplastic conditions. The use of electronic cigarettes (ECIGs), also known as electronic nicotine delivery devices, has increased significantly in recent years. Nicotine, propylene glycol, and / or glycerine, water, alcohol, flavorings, and other substances are among the many chemicals found in ECIGs that are vaporized and inhaled. A review of the existing literature shows that research dedicated to ECIGs is a rapidly developing and growing field of study. The rationale for the use of ECIGs is that they represent a safer alternative to traditional tobacco products. However, vaping safety profiles are still under development, as this is a relatively recent phenomenon. Various model organisms can be employed to examine the cellular processes that may be altered by exposure to the electronic liquids utilized for vaping. For example, the translucent multicellular eukaryote Caenorhabditis elegans is widely used as a model organism to explain a broad range of biological processes, including aging, stress response, development, and many others. Due to its short lifespan and easy use, C. elegans is an ideal model organism for studying chronic exposure to drugs and environmental toxicology. This review presents a summary of the most recent findings on the impact of electronic cigarettes on the physiological health of this nematode. Preliminary observations made in C. elegans can provide insight into the consequences of exposure to fundamental cellular physiology, which can then be used for future research in humans and mammalian models.http://www.sciencedirect.com/science/article/pii/S0147651325001897Electronic cigarettesE-cigaretteECIGsVapingCaenorhabditis elegans |
| spellingShingle | Kamila Melnikov Alžbeta Kaiglová Soňa Kucharíková The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes Ecotoxicology and Environmental Safety Electronic cigarettes E-cigarette ECIGs Vaping Caenorhabditis elegans |
| title | The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| title_full | The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| title_fullStr | The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| title_full_unstemmed | The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| title_short | The use of the model organism Caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| title_sort | use of the model organism caenorhabditis elegans in the investigation of the adverse effects of electronic cigarettes |
| topic | Electronic cigarettes E-cigarette ECIGs Vaping Caenorhabditis elegans |
| url | http://www.sciencedirect.com/science/article/pii/S0147651325001897 |
| work_keys_str_mv | AT kamilamelnikov theuseofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes AT alzbetakaiglova theuseofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes AT sonakucharikova theuseofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes AT kamilamelnikov useofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes AT alzbetakaiglova useofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes AT sonakucharikova useofthemodelorganismcaenorhabditiselegansintheinvestigationoftheadverseeffectsofelectroniccigarettes |