Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation

Central venous catheters (CVCs) are essential in neonatal care units to ensure prolonged venous access. Despite experienced CVC placement, managing fragile and small newborn vessels involves the risk of traumatic and iatrogenic complications. The most common include phlebitis, thrombosis, sepsis, an...

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Main Authors: Carolina Coramusi, Jessica F. Toro, Ramón G. Pabón, Mario Barreto, Giovanni Di Nardo, Pasquale Parisi, Claudia C. M. Marín
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pediatrics
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Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1602098/full
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author Carolina Coramusi
Jessica F. Toro
Ramón G. Pabón
Mario Barreto
Giovanni Di Nardo
Pasquale Parisi
Claudia C. M. Marín
author_facet Carolina Coramusi
Jessica F. Toro
Ramón G. Pabón
Mario Barreto
Giovanni Di Nardo
Pasquale Parisi
Claudia C. M. Marín
author_sort Carolina Coramusi
collection DOAJ
description Central venous catheters (CVCs) are essential in neonatal care units to ensure prolonged venous access. Despite experienced CVC placement, managing fragile and small newborn vessels involves the risk of traumatic and iatrogenic complications. The most common include phlebitis, thrombosis, sepsis, and catheter displacement. Rarely, catheter displacement may lead to fluid accumulation around serous membranes and adjacent organs, which, if not identified early, can even result in neonatal death. We report two cases: one of neonatal hydrothorax with subsequent lung cystic formation after a parenteral nutrition leakage caused by the displacement of an Epicutaneo-Caval Catheter in the basilic vein of the left arm; the second involves a peritoneal collection of parenteral nutrition from the umbilical venous catheter.
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spelling doaj-art-62c5966c41fe484ea7dd616763a05f3d2025-08-20T02:03:19ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-06-011310.3389/fped.2025.16020981602098Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasationCarolina Coramusi0Jessica F. Toro1Ramón G. Pabón2Mario Barreto3Giovanni Di Nardo4Pasquale Parisi5Claudia C. M. Marín6Unit of Pediatrics, Sant'Andrea University Hospital, Faculty of Medicine and Psychology, “Sapienza” University, Rome, ItalyClinica Medilaser Abner Lozano, Pediatric Infection Diseases, Faculty of Medicine UniNavarra University Foundation, Neiva, ColombiaClinica Medilaser Abner Lozano, Neonatal Intensive Care Unit, Faculty of Medicine, UniNavarra University Foundation, Neiva, ColombiaUnit of Pediatrics, Sant'Andrea University Hospital, Faculty of Medicine and Psychology, “Sapienza” University, Rome, ItalyUnit of Pediatrics, Sant'Andrea University Hospital, Faculty of Medicine and Psychology, “Sapienza” University, Rome, ItalyUnit of Pediatrics, Sant'Andrea University Hospital, Faculty of Medicine and Psychology, “Sapienza” University, Rome, ItalyClinica Medilaser Abner Lozano, Neonatal Intensive Care Unit, Faculty of Medicine, UniNavarra University Foundation, Neiva, ColombiaCentral venous catheters (CVCs) are essential in neonatal care units to ensure prolonged venous access. Despite experienced CVC placement, managing fragile and small newborn vessels involves the risk of traumatic and iatrogenic complications. The most common include phlebitis, thrombosis, sepsis, and catheter displacement. Rarely, catheter displacement may lead to fluid accumulation around serous membranes and adjacent organs, which, if not identified early, can even result in neonatal death. We report two cases: one of neonatal hydrothorax with subsequent lung cystic formation after a parenteral nutrition leakage caused by the displacement of an Epicutaneo-Caval Catheter in the basilic vein of the left arm; the second involves a peritoneal collection of parenteral nutrition from the umbilical venous catheter.https://www.frontiersin.org/articles/10.3389/fped.2025.1602098/fullnewbornumbilical venous catheterEpicutaneo-Caval Cathetercomplicationscystic lesionshydrothorax
spellingShingle Carolina Coramusi
Jessica F. Toro
Ramón G. Pabón
Mario Barreto
Giovanni Di Nardo
Pasquale Parisi
Claudia C. M. Marín
Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
Frontiers in Pediatrics
newborn
umbilical venous catheter
Epicutaneo-Caval Catheter
complications
cystic lesions
hydrothorax
title Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
title_full Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
title_fullStr Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
title_full_unstemmed Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
title_short Case Report: Uncommon complications of central catheters in newborns: two cases of parenteral nutrition extravasation
title_sort case report uncommon complications of central catheters in newborns two cases of parenteral nutrition extravasation
topic newborn
umbilical venous catheter
Epicutaneo-Caval Catheter
complications
cystic lesions
hydrothorax
url https://www.frontiersin.org/articles/10.3389/fped.2025.1602098/full
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