Non-functional parathyroid cyst - diagnostic pitfall: A case-report
Introduction. Parathyroid cysts are relative rare and they may be misdiagnosed with thyroid nodules. Parathyroid cysts are characterized by elevated level of parathyroid hormone (PTH) in cystic fluid. Case report. We reported about middle-aged woman with palpable node in the left thyroid lo...
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2015-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500103P.pdf |
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| author | Polovina Snežana P. Anđelković Zoran Micić Dragan D. |
| author_facet | Polovina Snežana P. Anđelković Zoran Micić Dragan D. |
| author_sort | Polovina Snežana P. |
| collection | DOAJ |
| description | Introduction. Parathyroid cysts are relative rare and they may be
misdiagnosed with thyroid nodules. Parathyroid cysts are characterized by
elevated level of parathyroid hormone (PTH) in cystic fluid. Case report. We
reported about middle-aged woman with palpable node in the left thyroid lobe.
Ultrasound showed anechoic 40 ´ 25 mm lesion in the left thyroid lobe. Fine
needle aspiration (FNA) obtained 13 mL colorless, watery cystic fluid. PTH
value in cystic fluid was ten fold more in comparison with serum PTH. Serum
PTH was slightly elevated, D vitamin was under the reference range, serum
calcium and phosphorus were normal as well as thyroid hormones. Thyroglobulin
antibodies (TgAb) and thyroid peroxidase antibodies (TPOAb) were not
detected. Radionuclide parathyroid scintigraphy indicated at physiological
metaiodbenzyl-guamidine (MIBG) distribution. After six months of vitamin D
supplementation, serum calcium, phosphorus, vitamin D and PTH were normal.
This finding was indicative that was a nonfunctional parathyroid cyst.
Conclusion. This case report points out that thyroid cystic lesions with thin
walls, and reverberation in ultrasound, must be observed as a potential
parathyroid cyst. These cysts require caution during diagnostic aspiration
because of danger of hypercalcemic crises due to FNA, which can be a
life-threatening condition. |
| format | Article |
| id | doaj-art-62aa6f7cfc144a81a02a29a364f819f6 |
| institution | DOAJ |
| issn | 0042-8450 2406-0720 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-62aa6f7cfc144a81a02a29a364f819f62025-08-20T03:19:29ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502406-07202015-01-0172111032103410.2298/VSP140624103P0042-84501500103PNon-functional parathyroid cyst - diagnostic pitfall: A case-reportPolovina Snežana P.0Anđelković Zoran1Micić Dragan D.2Clinical Center of Serbia, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Belgrade + Faculty of Medicine, BelgradeMilitary Medical Academy, Clinic for Endocrinology, BelgradeClinical Center of Serbia, Clinic for Endocrinology, Diabetes and Diseases of Metabolism, Belgrade + Faculty of Medicine, BelgradeIntroduction. Parathyroid cysts are relative rare and they may be misdiagnosed with thyroid nodules. Parathyroid cysts are characterized by elevated level of parathyroid hormone (PTH) in cystic fluid. Case report. We reported about middle-aged woman with palpable node in the left thyroid lobe. Ultrasound showed anechoic 40 ´ 25 mm lesion in the left thyroid lobe. Fine needle aspiration (FNA) obtained 13 mL colorless, watery cystic fluid. PTH value in cystic fluid was ten fold more in comparison with serum PTH. Serum PTH was slightly elevated, D vitamin was under the reference range, serum calcium and phosphorus were normal as well as thyroid hormones. Thyroglobulin antibodies (TgAb) and thyroid peroxidase antibodies (TPOAb) were not detected. Radionuclide parathyroid scintigraphy indicated at physiological metaiodbenzyl-guamidine (MIBG) distribution. After six months of vitamin D supplementation, serum calcium, phosphorus, vitamin D and PTH were normal. This finding was indicative that was a nonfunctional parathyroid cyst. Conclusion. This case report points out that thyroid cystic lesions with thin walls, and reverberation in ultrasound, must be observed as a potential parathyroid cyst. These cysts require caution during diagnostic aspiration because of danger of hypercalcemic crises due to FNA, which can be a life-threatening condition.http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500103P.pdfparathyroid diseasescystsbiopsy, fine needlehypercalcemia |
| spellingShingle | Polovina Snežana P. Anđelković Zoran Micić Dragan D. Non-functional parathyroid cyst - diagnostic pitfall: A case-report Vojnosanitetski Pregled parathyroid diseases cysts biopsy, fine needle hypercalcemia |
| title | Non-functional parathyroid cyst - diagnostic pitfall: A case-report |
| title_full | Non-functional parathyroid cyst - diagnostic pitfall: A case-report |
| title_fullStr | Non-functional parathyroid cyst - diagnostic pitfall: A case-report |
| title_full_unstemmed | Non-functional parathyroid cyst - diagnostic pitfall: A case-report |
| title_short | Non-functional parathyroid cyst - diagnostic pitfall: A case-report |
| title_sort | non functional parathyroid cyst diagnostic pitfall a case report |
| topic | parathyroid diseases cysts biopsy, fine needle hypercalcemia |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2015/0042-84501500103P.pdf |
| work_keys_str_mv | AT polovinasnezanap nonfunctionalparathyroidcystdiagnosticpitfallacasereport AT anđelkoviczoran nonfunctionalparathyroidcystdiagnosticpitfallacasereport AT micicdragand nonfunctionalparathyroidcystdiagnosticpitfallacasereport |