P. gingivalis alters lung microbiota and aggravates disease severity of COPD rats by up-regulating Hsp90α/MLKL

P. gingivalis alters lung microbiota and aggravates disease severity of COPD rats by up-regulating Hsp90α/MLKL

Background Epidemiological evidence has confirmed that periodontitis is an essential and independent risk factor of chronic obstructive pulmonary disease (COPD). Porphyromonas gingivalis, a major pathogen implicated in periodontitis, may make a vital contribution to COPD progression. However, the sp...

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Bibliographic Details
Main Authors: Nan Feng, Xuan Han, Da Peng, Fengxue Geng, Qian Li, Chunlin Pan, Hongyan Wang, Yaping Pan, Lisi Tan
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Journal of Oral Microbiology
Subjects:
Porphyromonas gingivalis
chronic obstructive pulmonary disease
lung microbiota
Hsp90α
MLKL
necroptosis
Online Access:https://www.tandfonline.com/doi/10.1080/20002297.2024.2334588
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