Anthelmintic activity on Haemonchus contortus and toxicity of benzoyl-carvacrol: a study in vitro, in silico and in vivo

Anthelmintic activity on Haemonchus contortus and toxicity of benzoyl-carvacrol: a study in vitro, in silico and in vivo

Abstract Carvacrol is isolated from essential oils and possesses activity against gastrointestinal nematodes of small ruminants. Benzoylation has been proposed to improve its pharmacological and pharmacokinetic properties. The objectives of this study were to evaluate the ovicidal activity of benzoy...

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Bibliographic Details
Main Authors: Andreza Pereira Braga, José Vilemar de Araújo Filho, Matheus Luiggi Freitas Barbosa, Raphael Ferreira Oliveira, Daniela Ribeiro Alves, Wildson Max Barbosa da Silva, Matheus Nunes da Rocha, Emmanuel Silva Marinho, Márcia Machado Marinho, Wesley Lyeverton Correia Ribeiro, Selene Maia de Morais, Claudia Maria Leal Bevilaqua, Lorena Mayana Beserra de Oliveira
Format: Article
Language:English
Published: Colégio Brasileiro de Parasitologia Veterinaria 2025-03-01
Series:Revista Brasileira de Parasitologia Veterinária
Subjects:
Carvacrol
benzoylation
β-tubulin
toxicological safety
gastrointestinal nematodes
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-29612025000200800&tlng=en
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