Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit
Background: Early diagnosis of sepsis can lead to rapid initiation of treatment and reduced mortality. The aim of this study was to investigate the relationship between eosinopenia and neutrophil-lymphocyte ratio (NLR) with sepsis-related mortality in the intensive care unit. Results: Out of 100 pat...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Babol University of Medical Sciences
2025-06-01
|
| Series: | Caspian Journal of Internal Medicine |
| Subjects: | |
| Online Access: | http://caspjim.com/article-1-3895-en.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849470977410334720 |
|---|---|
| author | Parviz Amri Armin Nejadnaderi Hemmat Gholinia Fatemeh Heidarnia Masomeh Bayani |
| author_facet | Parviz Amri Armin Nejadnaderi Hemmat Gholinia Fatemeh Heidarnia Masomeh Bayani |
| author_sort | Parviz Amri |
| collection | DOAJ |
| description | Background: Early diagnosis of sepsis can lead to rapid initiation of treatment and reduced mortality. The aim of this study was to investigate the relationship between eosinopenia and neutrophil-lymphocyte ratio (NLR) with sepsis-related mortality in the intensive care unit.
Results: Out of 100 patients studied, 59 patients survived and 41 patients died and the mean age of the patients was 63.27±16.13 years. Out of 40 patients with eosinopenia, 19(46.3%) died and out of 60 patients with normal eosinophil, 22(53.7%) died (P=0.28). The NLR on the first day in died patients was significantly higher than in the surviving patients (P=0.009). The increase in SOFA Score (p<0.001 and OR=1.49) and the increase in NLR (P=0.02 and OR=3.38) has a direct relationship with the mortality rate.
Conclusion: The results of the present study in sepsis patients showed that patients who had a higher neutrophil-to-lymphocyte ratio had higher mortality and there was no relationship between eosinopenia and mortality rate. |
| format | Article |
| id | doaj-art-628d96f153564892a5e697911b73e949 |
| institution | Kabale University |
| issn | 2008-6164 2008-6172 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Babol University of Medical Sciences |
| record_format | Article |
| series | Caspian Journal of Internal Medicine |
| spelling | doaj-art-628d96f153564892a5e697911b73e9492025-08-20T03:24:59ZengBabol University of Medical SciencesCaspian Journal of Internal Medicine2008-61642008-61722025-06-01163444450Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unitParviz Amri0Armin Nejadnaderi1Hemmat Gholinia2Fatemeh Heidarnia3Masomeh Bayani4 Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Student Research Committee, Babol University of Medical Sciences, Babol, Iran Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Clinical Research Development Unit of Ayatollah Rouhani Hospital, Faculty of Medicine, Babol University of Medical Sciences, Babol, Iran Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran Background: Early diagnosis of sepsis can lead to rapid initiation of treatment and reduced mortality. The aim of this study was to investigate the relationship between eosinopenia and neutrophil-lymphocyte ratio (NLR) with sepsis-related mortality in the intensive care unit. Results: Out of 100 patients studied, 59 patients survived and 41 patients died and the mean age of the patients was 63.27±16.13 years. Out of 40 patients with eosinopenia, 19(46.3%) died and out of 60 patients with normal eosinophil, 22(53.7%) died (P=0.28). The NLR on the first day in died patients was significantly higher than in the surviving patients (P=0.009). The increase in SOFA Score (p<0.001 and OR=1.49) and the increase in NLR (P=0.02 and OR=3.38) has a direct relationship with the mortality rate. Conclusion: The results of the present study in sepsis patients showed that patients who had a higher neutrophil-to-lymphocyte ratio had higher mortality and there was no relationship between eosinopenia and mortality rate.http://caspjim.com/article-1-3895-en.pdfmortalitysepsiseosinophilslymphocytesneutrophils |
| spellingShingle | Parviz Amri Armin Nejadnaderi Hemmat Gholinia Fatemeh Heidarnia Masomeh Bayani Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit Caspian Journal of Internal Medicine mortality sepsis eosinophils lymphocytes neutrophils |
| title | Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit |
| title_full | Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit |
| title_fullStr | Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit |
| title_full_unstemmed | Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit |
| title_short | Relationship between eosinopenia and neutrophil-lymphocyte ratio with sepsis-related mortality in the intensive care unit |
| title_sort | relationship between eosinopenia and neutrophil lymphocyte ratio with sepsis related mortality in the intensive care unit |
| topic | mortality sepsis eosinophils lymphocytes neutrophils |
| url | http://caspjim.com/article-1-3895-en.pdf |
| work_keys_str_mv | AT parvizamri relationshipbetweeneosinopeniaandneutrophillymphocyteratiowithsepsisrelatedmortalityintheintensivecareunit AT arminnejadnaderi relationshipbetweeneosinopeniaandneutrophillymphocyteratiowithsepsisrelatedmortalityintheintensivecareunit AT hemmatgholinia relationshipbetweeneosinopeniaandneutrophillymphocyteratiowithsepsisrelatedmortalityintheintensivecareunit AT fatemehheidarnia relationshipbetweeneosinopeniaandneutrophillymphocyteratiowithsepsisrelatedmortalityintheintensivecareunit AT masomehbayani relationshipbetweeneosinopeniaandneutrophillymphocyteratiowithsepsisrelatedmortalityintheintensivecareunit |