Deep learning for gender estimation using hand radiographs: a comparative evaluation of CNN models

Abstract Background Accurate gender estimation plays a crucial role in forensic identification, especially in mass disasters or cases involving fragmented or decomposed remains where traditional skeletal landmarks are unavailable. This study aimed to develop a deep learning-based model for gender cl...

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Bibliographic Details
Main Authors: Hilal Er Ulubaba, İpek Atik, Rukiye Çiftçi, Özgür Eken, Monira I. Aldhahi
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Imaging
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Online Access:https://doi.org/10.1186/s12880-025-01809-8
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Summary:Abstract Background Accurate gender estimation plays a crucial role in forensic identification, especially in mass disasters or cases involving fragmented or decomposed remains where traditional skeletal landmarks are unavailable. This study aimed to develop a deep learning-based model for gender classification using hand radiographs, offering a rapid and objective alternative to conventional methods. Methods We analyzed 470 left-hand X-ray images from adults aged 18 to 65 years using four convolutional neural network (CNN) architectures: ResNet-18, ResNet-50, InceptionV3, and EfficientNet-B0. Following image preprocessing and data augmentation, models were trained and validated using standard classification metrics: accuracy, precision, recall, and F1 score. Data augmentation included random rotation, horizontal flipping, and brightness adjustments to enhance model generalization. Results Among the tested models, ResNet-50 achieved the highest classification accuracy (93.2%) with precision of 92.4%, recall of 93.3%, and F1 score of 92.5%. While other models demonstrated acceptable performance, ResNet-50 consistently outperformed them across all metrics. These findings suggest CNNs can reliably extract sexually dimorphic features from hand radiographs. Conclusions Deep learning approaches, particularly ResNet-50, provide a robust, scalable, and efficient solution for gender prediction from hand X-ray images. This method may serve as a valuable tool in forensic scenarios where speed and reliability are critical. Future research should validate these findings across diverse populations and incorporate explainable AI techniques to enhance interpretability.
ISSN:1471-2342