Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review

We report the neurobehavioral aspects of the delayed encephalopathy of carbon monoxide (CO) intoxication in a 29 year old woman and review the literature. Four weeks after CO poisoning, the patient developed a frontal lobe syndrome, visuoperceptual impairment, and diffuse white matter lesions with a...

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Main Authors: M. F. Mendez, R. C. Doss
Format: Article
Language:English
Published: Wiley 1995-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.3233/BEN-1995-8107
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author M. F. Mendez
R. C. Doss
author_facet M. F. Mendez
R. C. Doss
author_sort M. F. Mendez
collection DOAJ
description We report the neurobehavioral aspects of the delayed encephalopathy of carbon monoxide (CO) intoxication in a 29 year old woman and review the literature. Four weeks after CO poisoning, the patient developed a frontal lobe syndrome, visuoperceptual impairment, and diffuse white matter lesions with an otherwise normal neurological examination. In contrast, patients with the classical syndrome also have a parkinsonian state or an akinetic–mute state. The delayed encephalopathy of CO poisoning usually results from demyelination of subcortical white matter, necrosis of the globus pallidus, or both. The clinical aspects, risk factors, neurobiological features, and therapy and prognosis are discussed.
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spelling doaj-art-6279adca1fc64db7921d43434c8f16032025-02-03T05:48:00ZengWileyBehavioural Neurology0953-41801875-85841995-01-0181475210.3233/BEN-1995-8107Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and ReviewM. F. Mendez0R. C. Doss1University of California at Los Angeles and Neurobehavior Unit, West Los Angeles Veterans Affairs Medical Center, Los Angeles, CA, USASt Paul-Ramsey Medical Center, USAWe report the neurobehavioral aspects of the delayed encephalopathy of carbon monoxide (CO) intoxication in a 29 year old woman and review the literature. Four weeks after CO poisoning, the patient developed a frontal lobe syndrome, visuoperceptual impairment, and diffuse white matter lesions with an otherwise normal neurological examination. In contrast, patients with the classical syndrome also have a parkinsonian state or an akinetic–mute state. The delayed encephalopathy of CO poisoning usually results from demyelination of subcortical white matter, necrosis of the globus pallidus, or both. The clinical aspects, risk factors, neurobiological features, and therapy and prognosis are discussed.http://dx.doi.org/10.3233/BEN-1995-8107
spellingShingle M. F. Mendez
R. C. Doss
Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
Behavioural Neurology
title Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
title_full Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
title_fullStr Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
title_full_unstemmed Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
title_short Neurobehavioral Aspects of the Delayed Encephalopathy of Carbon Monoxide Intoxication: Case Report and Review
title_sort neurobehavioral aspects of the delayed encephalopathy of carbon monoxide intoxication case report and review
url http://dx.doi.org/10.3233/BEN-1995-8107
work_keys_str_mv AT mfmendez neurobehavioralaspectsofthedelayedencephalopathyofcarbonmonoxideintoxicationcasereportandreview
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