HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY
Prevention and treatment of multi-organ failure after complicated surgeries on heart and major vessels remain to be crucial.The objective: to evaluate the potential use and efficiency of high-volume plasmapheresis for prevention and early therapy of multiple organ failure syndrome.Methods: high-volu...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2018-05-01
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| Series: | Вестник анестезиологии и реаниматологии |
| Subjects: | |
| Online Access: | https://www.vair-journal.com/jour/article/view/227 |
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| _version_ | 1849685531706785792 |
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| author | I. N. Solovievа Yu. V. Belov |
| author_facet | I. N. Solovievа Yu. V. Belov |
| author_sort | I. N. Solovievа |
| collection | DOAJ |
| description | Prevention and treatment of multi-organ failure after complicated surgeries on heart and major vessels remain to be crucial.The objective: to evaluate the potential use and efficiency of high-volume plasmapheresis for prevention and early therapy of multiple organ failure syndrome.Methods: high-volume plasmapheresis was used in 246 patients with the most disseminated complications of the peri-operative period. Plasmapheresis was done during the first 4–6 hours after surgery (157 patients) and in 6–12 hours after surgery (41 patients) and later than 12 hours (48 patients).Results. After complicated surgeries with in vitro hemoperfusion, the activation of system inflammatory response and endotoxicosis was more intensive versus patients with no complications. Plasmapheresis in 4–6 hours after surgery promoted metabolic normalization and in the majority of cases prevented of multiple organ failure (if at least 50% of circulating plasma was removed). After early plasmapheresis, the level of markers of system inflammatory response and endotoxicosis reduced by 28–30%, which allowed preventing serious renal disorders and cytolysis manifestations.Conclusion: Post-operative high-volume plasmapheresis performed in 4–6 hours after complicated cardiac surgeries is effective for prevention of multiple organ failure syndrome in 64% of cases. |
| format | Article |
| id | doaj-art-62782bde8224460db419548cda23802d |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2018-05-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-62782bde8224460db419548cda23802d2025-08-20T03:23:07ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-05-01152253110.21292/2078-5658-2018-15-2-25-31224HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERYI. N. Solovievа0Yu. V. Belov1B. V. Petrovsky Russian Research Surgery CenterB. V. Petrovsky Russian Research Surgery CenterPrevention and treatment of multi-organ failure after complicated surgeries on heart and major vessels remain to be crucial.The objective: to evaluate the potential use and efficiency of high-volume plasmapheresis for prevention and early therapy of multiple organ failure syndrome.Methods: high-volume plasmapheresis was used in 246 patients with the most disseminated complications of the peri-operative period. Plasmapheresis was done during the first 4–6 hours after surgery (157 patients) and in 6–12 hours after surgery (41 patients) and later than 12 hours (48 patients).Results. After complicated surgeries with in vitro hemoperfusion, the activation of system inflammatory response and endotoxicosis was more intensive versus patients with no complications. Plasmapheresis in 4–6 hours after surgery promoted metabolic normalization and in the majority of cases prevented of multiple organ failure (if at least 50% of circulating plasma was removed). After early plasmapheresis, the level of markers of system inflammatory response and endotoxicosis reduced by 28–30%, which allowed preventing serious renal disorders and cytolysis manifestations.Conclusion: Post-operative high-volume plasmapheresis performed in 4–6 hours after complicated cardiac surgeries is effective for prevention of multiple organ failure syndrome in 64% of cases.https://www.vair-journal.com/jour/article/view/227complicated cardiac and aortic surgeriesendogenous intoxicationprevention of multiple organ failurein vitro hemocorrectionhigh-volume plasmapheresis |
| spellingShingle | I. N. Solovievа Yu. V. Belov HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY Вестник анестезиологии и реаниматологии complicated cardiac and aortic surgeries endogenous intoxication prevention of multiple organ failure in vitro hemocorrection high-volume plasmapheresis |
| title | HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY |
| title_full | HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY |
| title_fullStr | HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY |
| title_full_unstemmed | HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY |
| title_short | HIGH-VOLUME PLASMAPHERESIS IN CARDIAC AND AORTIC SURGERY |
| title_sort | high volume plasmapheresis in cardiac and aortic surgery |
| topic | complicated cardiac and aortic surgeries endogenous intoxication prevention of multiple organ failure in vitro hemocorrection high-volume plasmapheresis |
| url | https://www.vair-journal.com/jour/article/view/227 |
| work_keys_str_mv | AT insolovieva highvolumeplasmapheresisincardiacandaorticsurgery AT yuvbelov highvolumeplasmapheresisincardiacandaorticsurgery |