Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing
Conclusion: Community-acquired MRSA clones are prevalent in the healthcare setting. The predominant genotype was t304 (10%), followed by t044 (7%) and t0127 (7%). The SCCmec IVd type was the most common type frequently associated with spa type t304, whereas SCCmec type IVc was primarily associated w...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
| Online Access: | http://dx.doi.org/10.1155/cjid/2753992 |
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| author | Mishaal Alanazi Hussein Aldughmani Farhan Alrowaili Fatma Alenazi Marzwq Alrewaili Mezna Alenazi Abdulhamid Alsalmi Hala M. Rushdy Khalid Almaary |
| author_facet | Mishaal Alanazi Hussein Aldughmani Farhan Alrowaili Fatma Alenazi Marzwq Alrewaili Mezna Alenazi Abdulhamid Alsalmi Hala M. Rushdy Khalid Almaary |
| author_sort | Mishaal Alanazi |
| collection | DOAJ |
| description | Conclusion: Community-acquired MRSA clones are prevalent in the healthcare setting. The predominant genotype was t304 (10%), followed by t044 (7%) and t0127 (7%). The SCCmec IVd type was the most common type frequently associated with spa type t304, whereas SCCmec type IVc was primarily associated with spa type t044. Isolates harboring SCCmec type IVd showed more nonsusceptible phenotypes to ciprofloxacin than other SCCmec types. Most MRSA isolates were resistant to erythromycin and clindamycin. These findings provide valuable insights into the molecular epidemiology of MRSA in the northern region of Saudi Arabia and highlight the prevalence of specific MRSA strains and their antibiotic resistance profiles. This information is essential for monitoring and addressing the spread of MRSA in healthcare settings. |
| format | Article |
| id | doaj-art-6274494980cb461f86ea74332df2e87f |
| institution | DOAJ |
| issn | 1918-1493 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases and Medical Microbiology |
| spelling | doaj-art-6274494980cb461f86ea74332df2e87f2025-08-20T03:22:04ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1918-14932025-01-01202510.1155/cjid/2753992Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa TypingMishaal Alanazi0Hussein Aldughmani1Farhan Alrowaili2Fatma Alenazi3Marzwq Alrewaili4Mezna Alenazi5Abdulhamid Alsalmi6Hala M. Rushdy7Khalid Almaary8Department of Laboratories and Blood BankDepartment of Laboratories and Blood BankDepartment of Laboratories and Blood BankDepartment of Laboratories and Blood BankDepartment of Central Sterile ServicesDepartment of Central Sterile ServicesDepartment of Laboratories and Blood BankGeneral Directorate of Infection Prevention & ControlDepartment of Botany & MicrobiologyConclusion: Community-acquired MRSA clones are prevalent in the healthcare setting. The predominant genotype was t304 (10%), followed by t044 (7%) and t0127 (7%). The SCCmec IVd type was the most common type frequently associated with spa type t304, whereas SCCmec type IVc was primarily associated with spa type t044. Isolates harboring SCCmec type IVd showed more nonsusceptible phenotypes to ciprofloxacin than other SCCmec types. Most MRSA isolates were resistant to erythromycin and clindamycin. These findings provide valuable insights into the molecular epidemiology of MRSA in the northern region of Saudi Arabia and highlight the prevalence of specific MRSA strains and their antibiotic resistance profiles. This information is essential for monitoring and addressing the spread of MRSA in healthcare settings.http://dx.doi.org/10.1155/cjid/2753992 |
| spellingShingle | Mishaal Alanazi Hussein Aldughmani Farhan Alrowaili Fatma Alenazi Marzwq Alrewaili Mezna Alenazi Abdulhamid Alsalmi Hala M. Rushdy Khalid Almaary Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing Canadian Journal of Infectious Diseases and Medical Microbiology |
| title | Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing |
| title_full | Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing |
| title_fullStr | Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing |
| title_full_unstemmed | Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing |
| title_short | Understanding the Molecular Epidemiology of Community-Acquired Methicillin-Resistant Staphylococcus aureus in Northern Saudi Arabia: A Spotlight on SCCmec and spa Typing |
| title_sort | understanding the molecular epidemiology of community acquired methicillin resistant staphylococcus aureus in northern saudi arabia a spotlight on sccmec and spa typing |
| url | http://dx.doi.org/10.1155/cjid/2753992 |
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