Sex-specific effects of predator scent stress on fear, anxiety-like behavior and methamphetamine seeking in rats

Sex-specific effects of predator scent stress on fear, anxiety-like behavior and methamphetamine seeking in rats

Methamphetamine use disorder (MUD) is frequently comorbid with other disorders, such as post-traumatic stress disorder (PTSD). Here, we used a rat model of PTSD+MUD to evaluate the influence of sex and stress on methamphetamine-seeking and on the activation of frontocortical regions during reinstate...

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Bibliographic Details
Main Authors: CG Modrak, CS Wilkinson, AD Claypool, AJ Moore, L Wu, LA Knackstedt, M Schwendt
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Addiction Neuroscience
Subjects:
Methamphetamine
Self-administration
Relapse
Predator scent stress
Anxiety
C-Fos
Online Access:http://www.sciencedirect.com/science/article/pii/S2772392525000112
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