Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues

The phenylpropanoid pathway remains a key target for most climate-resilient crop development, owing to it being a precursor to over 8000 metabolites, including flavonoids and lignin compounds, including their derivatives. These metabolites are involved in biotic and abiotic stress tolerance, invitin...

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Main Authors: Vincent Ninkuu, Oluwaseun Olayemi Aluko, Jianpei Yan, Hongmei Zeng, Guodao Liu, Jun Zhao, Huihui Li, Songbi Chen, Felix Dapare Dakora
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2025.1571825/full
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author Vincent Ninkuu
Vincent Ninkuu
Oluwaseun Olayemi Aluko
Jianpei Yan
Hongmei Zeng
Guodao Liu
Jun Zhao
Jun Zhao
Huihui Li
Huihui Li
Songbi Chen
Felix Dapare Dakora
Felix Dapare Dakora
author_facet Vincent Ninkuu
Vincent Ninkuu
Oluwaseun Olayemi Aluko
Jianpei Yan
Hongmei Zeng
Guodao Liu
Jun Zhao
Jun Zhao
Huihui Li
Huihui Li
Songbi Chen
Felix Dapare Dakora
Felix Dapare Dakora
author_sort Vincent Ninkuu
collection DOAJ
description The phenylpropanoid pathway remains a key target for most climate-resilient crop development, owing to it being a precursor to over 8000 metabolites, including flavonoids and lignin compounds, including their derivatives. These metabolites are involved in biotic and abiotic stress tolerance, inviting several studies into their roles in plant defense, drought, temperature, UV, and nutrient stress tolerance. Literature is currently inundated with cutting-edge reports on the phenylpropanoid pathways and their functions. Here, we provide a comprehensive update on the biosynthesis of phenylpropanoids, mainly lignin and flavonoids, their roles in biotic and abiotic interaction, and transcending topics, including pest and diseases, drought, temperature, and UV stress tolerance. We further reviewed the post-transcriptional, post-translational, and epigenetic modifications regulating phenylpropanoid metabolism and highlighted their applications and optimization strategies for large-scale production. This review provides an all-inclusive update on recent reports on the metabolism of phenylpropanoids in plants.
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institution Kabale University
issn 1664-462X
language English
publishDate 2025-06-01
publisher Frontiers Media S.A.
record_format Article
series Frontiers in Plant Science
spelling doaj-art-625bb1609fab4eccaa24d356f8920a132025-08-20T03:30:08ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2025-06-011610.3389/fpls.2025.15718251571825Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cuesVincent Ninkuu0Vincent Ninkuu1Oluwaseun Olayemi Aluko2Jianpei Yan3Hongmei Zeng4Guodao Liu5Jun Zhao6Jun Zhao7Huihui Li8Huihui Li9Songbi Chen10Felix Dapare Dakora11Felix Dapare Dakora12National Nanfan Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Sanya, ChinaState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaCrops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences/Key Laboratory of Ministry of Agriculture for Germplasm Resources, Conservation, and Utilization of Cassava, Danzhou, ChinaState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaCrops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences/Key Laboratory of Ministry of Agriculture for Germplasm Resources, Conservation, and Utilization of Cassava, Danzhou, ChinaNational Nanfan Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Sanya, ChinaBiotechnology Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Beijing, ChinaNational Nanfan Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Sanya, ChinaState Key Laboratory of Crop Gene Resources and Breeding, Institute of Crop Sciences, CAAS, Beijing, ChinaCrops Genetic Resources Institute, Chinese Academy of Tropical Agricultural Sciences/Key Laboratory of Ministry of Agriculture for Germplasm Resources, Conservation, and Utilization of Cassava, Danzhou, ChinaNational Nanfan Research Institute, Chinese Academy of Agricultural Sciences (CAAS), Sanya, ChinaChemistry Department, Tshwane University of Technology, Pretoria, South AfricaThe phenylpropanoid pathway remains a key target for most climate-resilient crop development, owing to it being a precursor to over 8000 metabolites, including flavonoids and lignin compounds, including their derivatives. These metabolites are involved in biotic and abiotic stress tolerance, inviting several studies into their roles in plant defense, drought, temperature, UV, and nutrient stress tolerance. Literature is currently inundated with cutting-edge reports on the phenylpropanoid pathways and their functions. Here, we provide a comprehensive update on the biosynthesis of phenylpropanoids, mainly lignin and flavonoids, their roles in biotic and abiotic interaction, and transcending topics, including pest and diseases, drought, temperature, and UV stress tolerance. We further reviewed the post-transcriptional, post-translational, and epigenetic modifications regulating phenylpropanoid metabolism and highlighted their applications and optimization strategies for large-scale production. This review provides an all-inclusive update on recent reports on the metabolism of phenylpropanoids in plants.https://www.frontiersin.org/articles/10.3389/fpls.2025.1571825/fullphenylpropanoidsplant interactionspost-transcriptionpost-translationepigenetics modificationsplant development
spellingShingle Vincent Ninkuu
Vincent Ninkuu
Oluwaseun Olayemi Aluko
Jianpei Yan
Hongmei Zeng
Guodao Liu
Jun Zhao
Jun Zhao
Huihui Li
Huihui Li
Songbi Chen
Felix Dapare Dakora
Felix Dapare Dakora
Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
Frontiers in Plant Science
phenylpropanoids
plant interactions
post-transcription
post-translation
epigenetics modifications
plant development
title Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
title_full Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
title_fullStr Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
title_full_unstemmed Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
title_short Phenylpropanoids metabolism: recent insight into stress tolerance and plant development cues
title_sort phenylpropanoids metabolism recent insight into stress tolerance and plant development cues
topic phenylpropanoids
plant interactions
post-transcription
post-translation
epigenetics modifications
plant development
url https://www.frontiersin.org/articles/10.3389/fpls.2025.1571825/full
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