Dysregulation of T Follicular Helper and Regulatory Cells in <i>IRF5</i>-SLE Homozygous Risk Carriers and Systemic Lupus Erythematosus Patients

T follicular helper (Tfh) and T follicular regulatory cells (Tfr) are required for antibody production and are dysregulated in SLE. Genetic variants within or near interferon regulatory factor 5 (<i>IRF5</i>) are associated with SLE risk. We previously reported higher plasma cells and au...

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Bibliographic Details
Main Authors: Bharati Matta, Lydia Thomas, Vinay Sharma, Betsy J. Barnes
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Cells
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Online Access:https://www.mdpi.com/2073-4409/14/6/454
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