Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales
Abstract Background Early intervention to slow childhood progression of myopia may improve quality of life and prevent future complications that burden individuals and healthcare systems. This study assessed the cost-effectiveness of myopia-control spectacles and contact lenses for the reduction of...
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| Language: | English |
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BMC
2025-06-01
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| Series: | Cost Effectiveness and Resource Allocation |
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| Online Access: | https://doi.org/10.1186/s12962-025-00632-w |
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| author | Hayley Bennett Andy Britton David O’Sullivan Francesca Lado |
| author_facet | Hayley Bennett Andy Britton David O’Sullivan Francesca Lado |
| author_sort | Hayley Bennett |
| collection | DOAJ |
| description | Abstract Background Early intervention to slow childhood progression of myopia may improve quality of life and prevent future complications that burden individuals and healthcare systems. This study assessed the cost-effectiveness of myopia-control spectacles and contact lenses for the reduction of myopia progression among children and adolescents in Wales. Methods A cost-utility analysis compared peripheral plus spectacle lenses (PPSL), multifocal soft contact lenses (MFSCL) and orthokeratology against single-vision correction. Efficacy and safety were informed by a Cochrane systemic review and meta-analyses. Quality-adjusted life years (QALYs) and costs incurred by NHS Wales were modelled over a lifetime horizon and discounted at 3.5%. Sensitivity analyses estimated uncertainty in incremental cost-effectiveness ratios (ICERs). Results PPSL was estimated to provide minimal benefit at a higher cost than single-vision correction. MFSCL gave a 0.28 QALY improvement at an additional cost of £4,040; corresponding to an ICER of £8,367 versus single-vision correction. Orthokeratology provided 0.5 QALYs at an additional cost of £3,732; corresponding to an ICER of £3,995 versus single-vision correction. In probabilistic sensitivity analysis, ICERs were below £20,000 in 71% and 90% of simulations for MFSCL and orthokeratology, respectively. Orthokeratology was the most cost-effective strategy in 76% of simulations. Cost-effectiveness was influenced by changes in progression rates, intervention costs and the utility of high myopia. However, orthokeratology remained the most cost-effective strategy throughout. Conclusions MFSCL and orthokeratology may be cost-effective options to slow the progression of myopia at thresholds applied in the UK. Further research is needed to understand the long-term effects of myopia-control interventions and their impact on quality of life. |
| format | Article |
| id | doaj-art-6251b8f84a064a3db4667e1ae6fe11c8 |
| institution | Kabale University |
| issn | 1478-7547 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | BMC |
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| series | Cost Effectiveness and Resource Allocation |
| spelling | doaj-art-6251b8f84a064a3db4667e1ae6fe11c82025-08-20T03:26:44ZengBMCCost Effectiveness and Resource Allocation1478-75472025-06-0123111010.1186/s12962-025-00632-wCost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in WalesHayley Bennett0Andy Britton1David O’Sullivan2Francesca Lado3Health Technology WalesOptometry WalesWelsh GovernmentNHS WalesAbstract Background Early intervention to slow childhood progression of myopia may improve quality of life and prevent future complications that burden individuals and healthcare systems. This study assessed the cost-effectiveness of myopia-control spectacles and contact lenses for the reduction of myopia progression among children and adolescents in Wales. Methods A cost-utility analysis compared peripheral plus spectacle lenses (PPSL), multifocal soft contact lenses (MFSCL) and orthokeratology against single-vision correction. Efficacy and safety were informed by a Cochrane systemic review and meta-analyses. Quality-adjusted life years (QALYs) and costs incurred by NHS Wales were modelled over a lifetime horizon and discounted at 3.5%. Sensitivity analyses estimated uncertainty in incremental cost-effectiveness ratios (ICERs). Results PPSL was estimated to provide minimal benefit at a higher cost than single-vision correction. MFSCL gave a 0.28 QALY improvement at an additional cost of £4,040; corresponding to an ICER of £8,367 versus single-vision correction. Orthokeratology provided 0.5 QALYs at an additional cost of £3,732; corresponding to an ICER of £3,995 versus single-vision correction. In probabilistic sensitivity analysis, ICERs were below £20,000 in 71% and 90% of simulations for MFSCL and orthokeratology, respectively. Orthokeratology was the most cost-effective strategy in 76% of simulations. Cost-effectiveness was influenced by changes in progression rates, intervention costs and the utility of high myopia. However, orthokeratology remained the most cost-effective strategy throughout. Conclusions MFSCL and orthokeratology may be cost-effective options to slow the progression of myopia at thresholds applied in the UK. Further research is needed to understand the long-term effects of myopia-control interventions and their impact on quality of life.https://doi.org/10.1186/s12962-025-00632-wCost effectivenessMyopiaNear-sightednessOptical devicesContact lensesOrthokeratology |
| spellingShingle | Hayley Bennett Andy Britton David O’Sullivan Francesca Lado Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales Cost Effectiveness and Resource Allocation Cost effectiveness Myopia Near-sightedness Optical devices Contact lenses Orthokeratology |
| title | Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales |
| title_full | Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales |
| title_fullStr | Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales |
| title_full_unstemmed | Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales |
| title_short | Cost-effectiveness of myopia-control spectacles and contact lenses for children and adolescents in Wales |
| title_sort | cost effectiveness of myopia control spectacles and contact lenses for children and adolescents in wales |
| topic | Cost effectiveness Myopia Near-sightedness Optical devices Contact lenses Orthokeratology |
| url | https://doi.org/10.1186/s12962-025-00632-w |
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