Effect of vitamin D supplementation on inflammatory status and behavioral symptoms in children with autism spectrum disorders: a double-blind randomized clinical trial

Effect of vitamin D supplementation on inflammatory status and behavioral symptoms in children with autism spectrum disorders: a double-blind randomized clinical trial

Abstract Purpose Inflammation in early childhood has been proposed as a clinically recognized risk factor for developing autism spectrum disorder (ASD). Since vitamin D has an anti-inflammatory role, this trial was aimed to evaluate the effects of vitamin D supplementation on TNF-α and IL-37 status...

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Main Authors: Zohreh Javadfar, Shahin Soltani, Firoozeh Khamoushi, Maryam Sharifi, Shima Moradi, Shahab Rezaeian, Ali Akbar Foroughi, Sahar Cheshmeh, Mehdi Taghaddosi, Fariborz Bahrehmand
Format: Article
Language:English
Published: BMC 2025-08-01
Series:BMC Pediatrics
Subjects:
Autism spectrum disorders
Vitamin d
Tumor necrosis factor-alpha
Interleukin-37
Behavioral symptoms
Online Access:https://doi.org/10.1186/s12887-025-05985-y
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