Remodeling the tumor immune microenvironment through hydrogel encapsulated G-Rh2 in situ vaccine and systemic immunotherapy

Remodeling the tumor immune microenvironment through hydrogel encapsulated G-Rh2 in situ vaccine and systemic immunotherapy

Ginsenoside Rh2 (G-Rh2) is a vital bioactive compound in Traditional Chinese Medicine, celebrated for its strong pharmacological properties, particularly its potent antitumor effects. However, its poor water solubility and limited bioavailability have necessitated the development of a novel drug del...

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Bibliographic Details
Main Authors: Chunhua Li, Dan Lei, Yudong Huang, Yuanhao Jing, Wanru Wang, Lanqi Cen, Zijian Wei, Anni Chen, Xiaoyu Feng, Yushu Wang, Lixia Yu, Ying Chen, Rutian Li
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Ginsenoside Rh2
PD-1 monoclonal antibody
Hydrogel
In situ vaccination
Tumor microenvironment
Immune modulation
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424003429
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