TAp73 modulates proliferation and ferroptosis in mammary epithelial cells

TAp73 modulates proliferation and ferroptosis in mammary epithelial cells

IntroductionTAp73, a transcriptionally active isoform of the p73 gene, is essential for epithelial tissue development. Ferroptosis, a regulated form of cell death characterized by lipid peroxidation and reactive oxygen species (ROS) accumulation, has been increasingly studied in recent years. Howeve...

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Bibliographic Details
Main Authors: Wenqiang Sun, Hanjun Ren, Le Chen, Bingfei Zhang, Liping Mei, Jiaqi Wen, Yilu Zhang, Jiaqi Li, Yongping Yan, Songjia Lai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
TAp73
mammary epithelial cells
cell death
ferroptosis
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1532910/full
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