MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD

Aim: To study blood rheological properties in the immediate postoperative period after the surgery due to ascending colon cancer. Materials and Methods: We recruited 145 consecutive patients (50-75 years of age) who underwent surgery due to ascending colon cancer. All p...

Full description

Saved in:
Bibliographic Details
Main Authors: Vladimir V. Maslyakov, Viatcheslav Y. Leontiev
Format: Article
Language:Russian
Published: Kemerovo State Medical University 2016-09-01
Series:Фундаментальная и клиническая медицина
Online Access:https://fcm.kemsmu.ru/jour/article/view/16
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849344577380548608
author Vladimir V. Maslyakov
Viatcheslav Y. Leontiev
author_facet Vladimir V. Maslyakov
Viatcheslav Y. Leontiev
author_sort Vladimir V. Maslyakov
collection DOAJ
description Aim: To study blood rheological properties in the immediate postoperative period after the surgery due to ascending colon cancer. Materials and Methods: We recruited 145 consecutive patients (50-75 years of age) who underwent surgery due to ascending colon cancer. All patients were divided into three groups: 1) T1N0M0 disease stage (n = 45); 2) T2N0M0 (n = 38); 3) T3N1M0 (n = 62). To determine blood rheological properties, we measured viscosity, deformation and aggregation of red blood cells. Results: We found that 1-3 days postoperation blood rheological properties, i.e. deformation and aggregation of red blood cells, hematocrit, and oxygen delivery to tissues, were increased in all groups with the further decline 5-7 and particularly 11-13 days postoperation. However, in patients with T2N0M0 and T3N1M0 stages, rheological properties did not return to the reference values. Conclusion: Alterations of rheological properties may have clinical significance in immediate postoperative period.
format Article
id doaj-art-6217dccfeb294dfe9041eef000758769
institution Kabale University
issn 2500-0764
2542-0941
language Russian
publishDate 2016-09-01
publisher Kemerovo State Medical University
record_format Article
series Фундаментальная и клиническая медицина
spelling doaj-art-6217dccfeb294dfe9041eef0007587692025-08-20T03:42:38ZrusKemerovo State Medical UniversityФундаментальная и клиническая медицина2500-07642542-09412016-09-0113525715MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIODVladimir V. Maslyakov0Viatcheslav Y. Leontiev1Saratov Medical University «Reaviz»Saratov Medical University «Reaviz»Aim: To study blood rheological properties in the immediate postoperative period after the surgery due to ascending colon cancer. Materials and Methods: We recruited 145 consecutive patients (50-75 years of age) who underwent surgery due to ascending colon cancer. All patients were divided into three groups: 1) T1N0M0 disease stage (n = 45); 2) T2N0M0 (n = 38); 3) T3N1M0 (n = 62). To determine blood rheological properties, we measured viscosity, deformation and aggregation of red blood cells. Results: We found that 1-3 days postoperation blood rheological properties, i.e. deformation and aggregation of red blood cells, hematocrit, and oxygen delivery to tissues, were increased in all groups with the further decline 5-7 and particularly 11-13 days postoperation. However, in patients with T2N0M0 and T3N1M0 stages, rheological properties did not return to the reference values. Conclusion: Alterations of rheological properties may have clinical significance in immediate postoperative period.https://fcm.kemsmu.ru/jour/article/view/16
spellingShingle Vladimir V. Maslyakov
Viatcheslav Y. Leontiev
MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
Фундаментальная и клиническая медицина
title MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
title_full MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
title_fullStr MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
title_full_unstemmed MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
title_short MICROCIRCULATION IN PATIENTS WITH ASCENDING COLON CANCER IN IMMEDIATE POSTOPERATIVE PERIOD
title_sort microcirculation in patients with ascending colon cancer in immediate postoperative period
url https://fcm.kemsmu.ru/jour/article/view/16
work_keys_str_mv AT vladimirvmaslyakov microcirculationinpatientswithascendingcoloncancerinimmediatepostoperativeperiod
AT viatcheslavyleontiev microcirculationinpatientswithascendingcoloncancerinimmediatepostoperativeperiod