Liquiritigenin ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function, reducing endoplasmic reticulum stress and modulating gut microbiota

Liquiritigenin ameliorates DSS-induced ulcerative colitis by improving intestinal barrier function, reducing endoplasmic reticulum stress and modulating gut microbiota

Inflammatory bowel disease remains a high recurrence rate and broad populations all over the world. Liquiritigenin isolated from licorice possess anti-inflammatory and antioxidative activities, suggesting its potential of treating ulcerative colitis (UC). In this study, we explored the effect of ora...

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Bibliographic Details
Main Authors: Luyao Liu, Fan Zhao, Dandan Han, Xin Lü, Gang Wu, Yanglei Yi
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Journal of Functional Foods
Subjects:
Polyphenolic flavonoids
Intestinal flora
Intestinal barrier
Ulcerative colitis
Endoplasmic reticulum stress (ER stress)
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464624005437
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