Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq
Abstract Background Diabetes mellitus (DM) is a global health challenge, requiring efficient management strategies. Monitoring biochemical markers such as lipid profiles and glycated hemoglobin (HbA1c) is critical in assessing disease progression and guiding treatment. While the individual importanc...
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SpringerOpen
2025-05-01
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| Series: | The Egyptian Journal of Internal Medicine |
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| Online Access: | https://doi.org/10.1186/s43162-025-00460-7 |
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| author | Lina N. Adam |
| author_facet | Lina N. Adam |
| author_sort | Lina N. Adam |
| collection | DOAJ |
| description | Abstract Background Diabetes mellitus (DM) is a global health challenge, requiring efficient management strategies. Monitoring biochemical markers such as lipid profiles and glycated hemoglobin (HbA1c) is critical in assessing disease progression and guiding treatment. While the individual importance of lipid profiles and HbA1c is well-established, understanding their relationship is increasingly relevant. Methods This cross-sectional study explored the association between HbA1c levels and lipid profiles in 128 diabetic patients, aged 18 to 83, from Zakho General Hospital, Kurdistan, Iraq. Results Statistical analysis revealed a mean age of 53.27 years and an average BMI of 29.10 kg/m2, indicating overweight and obesity. The mean HbA1c was 9.126%, reflecting poor glycemic control. Lipid profiles showed elevated triglycerides (230.8 mg/dL), LDL-c (110.2 mg/dL), and VLDL (48.54 mg/dL), indicating dyslipidemia. Significant positive correlations were observed between systolic blood pressure and both HbA1c (r = 0.2248, p = 0.0108) and Fasting blood glucose levels (r = 0.1929, p = 0.0291). LDL-c showed a significant negative correlation with age (r = -0.2360, p = 0.0073). Conclusions These results highlight the complex relationship between lipid metabolism and glycemic control, underscoring the need for integrated management approaches to improve patient outcomes in diabetes care. Trial registration 01012024–01-01. Registered 1- Jan 2023. |
| format | Article |
| id | doaj-art-620b362c5fc847e091042fa3d871c75e |
| institution | OA Journals |
| issn | 2090-9098 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Internal Medicine |
| spelling | doaj-art-620b362c5fc847e091042fa3d871c75e2025-08-20T02:03:34ZengSpringerOpenThe Egyptian Journal of Internal Medicine2090-90982025-05-013711610.1186/s43162-025-00460-7Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, IraqLina N. Adam0Department of Biology, College of Science, University of ZakhoAbstract Background Diabetes mellitus (DM) is a global health challenge, requiring efficient management strategies. Monitoring biochemical markers such as lipid profiles and glycated hemoglobin (HbA1c) is critical in assessing disease progression and guiding treatment. While the individual importance of lipid profiles and HbA1c is well-established, understanding their relationship is increasingly relevant. Methods This cross-sectional study explored the association between HbA1c levels and lipid profiles in 128 diabetic patients, aged 18 to 83, from Zakho General Hospital, Kurdistan, Iraq. Results Statistical analysis revealed a mean age of 53.27 years and an average BMI of 29.10 kg/m2, indicating overweight and obesity. The mean HbA1c was 9.126%, reflecting poor glycemic control. Lipid profiles showed elevated triglycerides (230.8 mg/dL), LDL-c (110.2 mg/dL), and VLDL (48.54 mg/dL), indicating dyslipidemia. Significant positive correlations were observed between systolic blood pressure and both HbA1c (r = 0.2248, p = 0.0108) and Fasting blood glucose levels (r = 0.1929, p = 0.0291). LDL-c showed a significant negative correlation with age (r = -0.2360, p = 0.0073). Conclusions These results highlight the complex relationship between lipid metabolism and glycemic control, underscoring the need for integrated management approaches to improve patient outcomes in diabetes care. Trial registration 01012024–01-01. Registered 1- Jan 2023.https://doi.org/10.1186/s43162-025-00460-7Diabetes mellitusLipid profileGlycated hemoglobin (HbA1c)Clinical parametersGlycemic control |
| spellingShingle | Lina N. Adam Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq The Egyptian Journal of Internal Medicine Diabetes mellitus Lipid profile Glycated hemoglobin (HbA1c) Clinical parameters Glycemic control |
| title | Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq |
| title_full | Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq |
| title_fullStr | Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq |
| title_full_unstemmed | Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq |
| title_short | Association between dyslipidemia and glycated hemoglobin in diabetic patients from Zakho General Hospital, Iraq |
| title_sort | association between dyslipidemia and glycated hemoglobin in diabetic patients from zakho general hospital iraq |
| topic | Diabetes mellitus Lipid profile Glycated hemoglobin (HbA1c) Clinical parameters Glycemic control |
| url | https://doi.org/10.1186/s43162-025-00460-7 |
| work_keys_str_mv | AT linanadam associationbetweendyslipidemiaandglycatedhemoglobinindiabeticpatientsfromzakhogeneralhospitaliraq |