"Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry
The calibration dependence of dicentrics and rings chromosomes with an accompanying fragment induction in human lymphocytes by in vitro 137Сs acute gamma irradiation of blood in the dose range of 0.09 - 1.0 Gy is presented. The application of the obtained calibration curve for estimation of “biologi...
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| Format: | Article |
| Language: | English |
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Institute for Nuclear Research, National Academy of Sciences of Ukraine
2021-06-01
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| Series: | Ядерна фізика та енергетика |
| Subjects: | |
| Online Access: | http://jnpae.kinr.kiev.ua/22.2/Articles_PDF/jnpae-2021-22-0167-Kurochkina.pdf |
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| author | V. A. Kurochkina L. K. Bezdrobna T. V. Tsyganok I. A. Khomych |
| author_facet | V. A. Kurochkina L. K. Bezdrobna T. V. Tsyganok I. A. Khomych |
| author_sort | V. A. Kurochkina |
| collection | DOAJ |
| description | The calibration dependence of dicentrics and rings chromosomes with an accompanying fragment induction in human lymphocytes by in vitro 137Сs acute gamma irradiation of blood in the dose range of 0.09 - 1.0 Gy is presented. The application of the obtained calibration curve for estimation of “biological” doses for overexposed 9 persons from the contract staff of the Chornobyl SSE is shown. Their doses calculated by the frequency of dicentrics and centric rings with consideration of operation duration and mode in the zone of influence of the radiation factor, significantly exceeded the doses determined by the methods of physical dosimetry. |
| format | Article |
| id | doaj-art-620400cc6d3a4ca0846cd64d72b6548e |
| institution | OA Journals |
| issn | 1818-331X 2074-0565 |
| language | English |
| publishDate | 2021-06-01 |
| publisher | Institute for Nuclear Research, National Academy of Sciences of Ukraine |
| record_format | Article |
| series | Ядерна фізика та енергетика |
| spelling | doaj-art-620400cc6d3a4ca0846cd64d72b6548e2025-08-20T02:24:01ZengInstitute for Nuclear Research, National Academy of Sciences of UkraineЯдерна фізика та енергетика1818-331X2074-05652021-06-01222167173https://doi.org/10.15407/jnpae2021.02.167"Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetryV. A. Kurochkina0L. K. Bezdrobna1T. V. Tsyganok2I. A. Khomych3Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, UkraineInstitute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, UkraineInstitute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, UkraineInstitute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, UkraineThe calibration dependence of dicentrics and rings chromosomes with an accompanying fragment induction in human lymphocytes by in vitro 137Сs acute gamma irradiation of blood in the dose range of 0.09 - 1.0 Gy is presented. The application of the obtained calibration curve for estimation of “biological” doses for overexposed 9 persons from the contract staff of the Chornobyl SSE is shown. Their doses calculated by the frequency of dicentrics and centric rings with consideration of operation duration and mode in the zone of influence of the radiation factor, significantly exceeded the doses determined by the methods of physical dosimetry.http://jnpae.kinr.kiev.ua/22.2/Articles_PDF/jnpae-2021-22-0167-Kurochkina.pdf137сsgamma irradiationhuman blood lymphocytesdicentrics and centric ringscalibration curvebiological dosimetry. |
| spellingShingle | V. A. Kurochkina L. K. Bezdrobna T. V. Tsyganok I. A. Khomych "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry Ядерна фізика та енергетика 137сs gamma irradiation human blood lymphocytes dicentrics and centric rings calibration curve biological dosimetry. |
| title | "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry |
| title_full | "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry |
| title_fullStr | "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry |
| title_full_unstemmed | "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry |
| title_short | "Dose – effect" calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137Сs in low doses for biological dosimetry |
| title_sort | dose effect calibration dependence by frequency of unstable chromosomic exchanges in human lymphocytes in acute gamma irradiation by 137сs in low doses for biological dosimetry |
| topic | 137сs gamma irradiation human blood lymphocytes dicentrics and centric rings calibration curve biological dosimetry. |
| url | http://jnpae.kinr.kiev.ua/22.2/Articles_PDF/jnpae-2021-22-0167-Kurochkina.pdf |
| work_keys_str_mv | AT vakurochkina doseeffectcalibrationdependencebyfrequencyofunstablechromosomicexchangesinhumanlymphocytesinacutegammairradiationby137ssinlowdosesforbiologicaldosimetry AT lkbezdrobna doseeffectcalibrationdependencebyfrequencyofunstablechromosomicexchangesinhumanlymphocytesinacutegammairradiationby137ssinlowdosesforbiologicaldosimetry AT tvtsyganok doseeffectcalibrationdependencebyfrequencyofunstablechromosomicexchangesinhumanlymphocytesinacutegammairradiationby137ssinlowdosesforbiologicaldosimetry AT iakhomych doseeffectcalibrationdependencebyfrequencyofunstablechromosomicexchangesinhumanlymphocytesinacutegammairradiationby137ssinlowdosesforbiologicaldosimetry |