Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen

Thermolysis of 4-arylthio- and 4-benzylthio-3-oxazolin-5-ones leads to arylthio- and benzylthio-substituted nitrile ylides, which undergo 1,3-dipolar cycloadditions with reactive dipolarophiles to give 5-membered aza-heterocycles (Schemes 1 and 2). In the absence of reactive dipolarophiles, the nit...

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Main Authors: Peter Wipf, Heinz Heimgartner
Format: Article
Language:deu
Published: Swiss Chemical Society 1984-10-01
Series:CHIMIA
Online Access:https://www.chimia.ch/chimia/article/view/9624
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author Peter Wipf
Heinz Heimgartner
author_facet Peter Wipf
Heinz Heimgartner
author_sort Peter Wipf
collection DOAJ
description Thermolysis of 4-arylthio- and 4-benzylthio-3-oxazolin-5-ones leads to arylthio- and benzylthio-substituted nitrile ylides, which undergo 1,3-dipolar cycloadditions with reactive dipolarophiles to give 5-membered aza-heterocycles (Schemes 1 and 2). In the absence of reactive dipolarophiles, the nitrile ylides isomerize to 2-aza-butadienes, which can be trapped by ethyl propiolate to yield pyridine derivatives (Scheme 3).
format Article
id doaj-art-61fc6b0d795e4fb3b42dcc3d458740a2
institution OA Journals
issn 0009-4293
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language deu
publishDate 1984-10-01
publisher Swiss Chemical Society
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spelling doaj-art-61fc6b0d795e4fb3b42dcc3d458740a22025-08-20T02:29:52ZdeuSwiss Chemical SocietyCHIMIA0009-42932673-24241984-10-01381010.2533/chimia.1984.357Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onenPeter Wipf0Heinz Heimgartner1Organisch-chemisches Institut der Universität Zürich, Winterthurerstrasse 190, CH-8057 ZürichOrganisch-chemisches Institut der Universität Zürich, Winterthurerstrasse 190, CH-8057 Zürich Thermolysis of 4-arylthio- and 4-benzylthio-3-oxazolin-5-ones leads to arylthio- and benzylthio-substituted nitrile ylides, which undergo 1,3-dipolar cycloadditions with reactive dipolarophiles to give 5-membered aza-heterocycles (Schemes 1 and 2). In the absence of reactive dipolarophiles, the nitrile ylides isomerize to 2-aza-butadienes, which can be trapped by ethyl propiolate to yield pyridine derivatives (Scheme 3). https://www.chimia.ch/chimia/article/view/9624
spellingShingle Peter Wipf
Heinz Heimgartner
Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
CHIMIA
title Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
title_full Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
title_fullStr Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
title_full_unstemmed Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
title_short Arylthio-substituierte Nitrilylide aus der Thermolyse von 4-Arylthio-3-oxazolin-5-onen
title_sort arylthio substituierte nitrilylide aus der thermolyse von 4 arylthio 3 oxazolin 5 onen
url https://www.chimia.ch/chimia/article/view/9624
work_keys_str_mv AT peterwipf arylthiosubstituiertenitrilylideausderthermolysevon4arylthio3oxazolin5onen
AT heinzheimgartner arylthiosubstituiertenitrilylideausderthermolysevon4arylthio3oxazolin5onen