The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo
Implantable biomaterials are extensively used to promote bone regeneration or support endosseous prosthesis in orthopedics and dentistry. Their use, however, would benefit from additional strategies to improve bone responses. Pulsed Electromagnetic Fields (PEMFs) have long been known to act on osteo...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
|
| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2018/8935750 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832559693753483264 |
|---|---|
| author | Carlo Galli Giuseppe Pedrazzi Monica Mattioli-Belmonte Stefano Guizzardi |
| author_facet | Carlo Galli Giuseppe Pedrazzi Monica Mattioli-Belmonte Stefano Guizzardi |
| author_sort | Carlo Galli |
| collection | DOAJ |
| description | Implantable biomaterials are extensively used to promote bone regeneration or support endosseous prosthesis in orthopedics and dentistry. Their use, however, would benefit from additional strategies to improve bone responses. Pulsed Electromagnetic Fields (PEMFs) have long been known to act on osteoblasts and bone, affecting their metabolism, in spite of our poor understanding of the underlying mechanisms. Hence, we have the hypothesis that PEMFs may also ameliorate cell responses to biomaterials, improving their growth, differentiation, and the expression of a mature phenotype and therefore increasing the tissue integration of the implanted devices and their clinical success. A broad range of settings used for PEMFs stimulation still represents a hurdle to better define treatment protocols and extensive research is needed to overcome this issue. The present review includes studies that investigated the effects of PEMFs on the response of bone cells to different classes of biomaterials and the reports that focused on in vivo investigations of biomaterials implanted in bone. |
| format | Article |
| id | doaj-art-61fa34caec104efaa94b1e6c8171fd50 |
| institution | Kabale University |
| issn | 1687-8787 1687-8795 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-61fa34caec104efaa94b1e6c8171fd502025-02-03T01:29:23ZengWileyInternational Journal of Biomaterials1687-87871687-87952018-01-01201810.1155/2018/89357508935750The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In VivoCarlo Galli0Giuseppe Pedrazzi1Monica Mattioli-Belmonte2Stefano Guizzardi3Dep. of Medicine and Surgery, University of Parma, ItalyDep. of Medicine and Surgery, University of Parma, ItalyDISCLIMO, Department of Clinical and Molecular Sciences, Polytechnic University of Marche, Ancona, ItalyDep. of Medicine and Surgery, University of Parma, ItalyImplantable biomaterials are extensively used to promote bone regeneration or support endosseous prosthesis in orthopedics and dentistry. Their use, however, would benefit from additional strategies to improve bone responses. Pulsed Electromagnetic Fields (PEMFs) have long been known to act on osteoblasts and bone, affecting their metabolism, in spite of our poor understanding of the underlying mechanisms. Hence, we have the hypothesis that PEMFs may also ameliorate cell responses to biomaterials, improving their growth, differentiation, and the expression of a mature phenotype and therefore increasing the tissue integration of the implanted devices and their clinical success. A broad range of settings used for PEMFs stimulation still represents a hurdle to better define treatment protocols and extensive research is needed to overcome this issue. The present review includes studies that investigated the effects of PEMFs on the response of bone cells to different classes of biomaterials and the reports that focused on in vivo investigations of biomaterials implanted in bone.http://dx.doi.org/10.1155/2018/8935750 |
| spellingShingle | Carlo Galli Giuseppe Pedrazzi Monica Mattioli-Belmonte Stefano Guizzardi The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo International Journal of Biomaterials |
| title | The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo |
| title_full | The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo |
| title_fullStr | The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo |
| title_full_unstemmed | The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo |
| title_short | The Use of Pulsed Electromagnetic Fields to Promote Bone Responses to Biomaterials In Vitro and In Vivo |
| title_sort | use of pulsed electromagnetic fields to promote bone responses to biomaterials in vitro and in vivo |
| url | http://dx.doi.org/10.1155/2018/8935750 |
| work_keys_str_mv | AT carlogalli theuseofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT giuseppepedrazzi theuseofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT monicamattiolibelmonte theuseofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT stefanoguizzardi theuseofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT carlogalli useofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT giuseppepedrazzi useofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT monicamattiolibelmonte useofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo AT stefanoguizzardi useofpulsedelectromagneticfieldstopromoteboneresponsestobiomaterialsinvitroandinvivo |