Burrowing Behavior as Robust Parameter for Early Humane Endpoint Determination in Murine Models for Pancreatic Cancer

Burrowing Behavior as Robust Parameter for Early Humane Endpoint Determination in Murine Models for Pancreatic Cancer

Due to late-stage diagnoses and limited treatment options, pancreatic cancer is predicted to be the second leading cause of cancer deaths by 2030. Many different murine models were developed over the past decades to test new therapies for this tumor entity. The laws and regulations demand the contin...

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Bibliographic Details
Main Authors: Jakob Brandstetter, Lisa Hoffmann, Ingo Koopmann, Tim Schreiber, Benjamin Schulz, Stephan Patrick Rosshart, Dietmar Zechner, Brigitte Vollmar, Simone Kumstel
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Animals
Subjects:
animal welfare
refinement
early humane endpoint
pancreatic cancer
Online Access:https://www.mdpi.com/2076-2615/15/9/1241
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