Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response

Immunodiagnostic plasma amino acid residue biomarkers detect cancer early and predict treatment response

Abstract The immune response to tumour development is frequently targeted with therapeutics but remains largely unexplored in diagnostics, despite being stronger for early-stage tumours. We present an immunodiagnostic platform to detect this. We identify a panel of amino acid residue biomarkers prov...

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Main Authors: Cong Tang, Patrícia Corredeira, Sandra Casimiro, Qi Shi, Qiwei Han, Wesley Sukdao, Ana Cavaco, Cecília Melo-Alvim, Carolina Ochôa Matos, Catarina Abreu, Steven Walsh, Gonçalo Nogueira-Costa, Leonor Ribeiro, Rita Sousa, Ana Lorena Barradas, João Eurico Fonseca, Luís Costa, Emma V. Yates, Gonçalo J. L. Bernardes
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61685-2
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