Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran

Background and Objective: Brucellosis is a zoonotic disease common in the Middle East, including Iran. Musculoskeletal manifestations, particularly in the spine, are frequent symptoms of brucellosis, often leading to delays in diagnosis due to its varied and non-specific symptoms. The present study...

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Main Authors: Peyman Eini, Narmin Karimian, Azar Pirdehghan, Pooya Eini
Format: Article
Language:fas
Published: Hamadan University of Medical Sciences 2024-12-01
Series:پزشکی بالینی ابن سینا
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Online Access:http://sjh.umsha.ac.ir/article-1-3086-en.pdf
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author Peyman Eini
Narmin Karimian
Azar Pirdehghan
Pooya Eini
author_facet Peyman Eini
Narmin Karimian
Azar Pirdehghan
Pooya Eini
author_sort Peyman Eini
collection DOAJ
description Background and Objective: Brucellosis is a zoonotic disease common in the Middle East, including Iran. Musculoskeletal manifestations, particularly in the spine, are frequent symptoms of brucellosis, often leading to delays in diagnosis due to its varied and non-specific symptoms. The present study aimed to investigate the prevalence, clinical presentation, and diagnostic challenges of musculoskeletal brucellosis, focusing on spinal involvement. Materials and Methods: This retrospective study reviewed the medical records of 782 patients with brucellosis admitted to Sina Hospital in Hamadan, Iran, from 2011 to 2020. Results: The results indicated that a significant portion (87.6%) of the patients had a history of consuming unpasteurized dairy products, and more than half (57.2%) had been exposed to livestock in the past year. The most common clinical symptoms were weakness and fatigue (66.7%), joint pain (62.7%), and fever (73.1%), while back pain (65.7%) and knee pain (48.3%) were the dominant musculoskeletal symptoms. In addition, arthritis (24.4%), spondylitis (15.4%), and sacroiliitis (13.4%) were the primary identified musculoskeletal complications. Conclusion: The clinical manifestations of brucellosis include common symptoms, such as fever, weakness, fatigue, and joint pain, which were more prevalent in male patients. In addition, musculoskeletal complications are prominent features of the disease. According to bone scan and MRI results, approximately 20% of hospitalized brucellosis patients had bone-joint complications, including arthritis, spondylitis, and sacroiliitis.
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series پزشکی بالینی ابن سینا
spelling doaj-art-61cbd39ef4154e779e7268be9c7651d72025-08-20T02:40:21ZfasHamadan University of Medical Sciencesپزشکی بالینی ابن سینا2588-722X2588-72382024-12-01313190196Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, IranPeyman Eini0Narmin Karimian1Azar Pirdehghan2Pooya Eini3 Infectious Disease Research Center, Hamadan University of Medical Sciences, Hamadan, Iran School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Department of Community Medicine, Hamadan University of Medical Sciences, Hamadan, Iran Toxicological Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran Background and Objective: Brucellosis is a zoonotic disease common in the Middle East, including Iran. Musculoskeletal manifestations, particularly in the spine, are frequent symptoms of brucellosis, often leading to delays in diagnosis due to its varied and non-specific symptoms. The present study aimed to investigate the prevalence, clinical presentation, and diagnostic challenges of musculoskeletal brucellosis, focusing on spinal involvement. Materials and Methods: This retrospective study reviewed the medical records of 782 patients with brucellosis admitted to Sina Hospital in Hamadan, Iran, from 2011 to 2020. Results: The results indicated that a significant portion (87.6%) of the patients had a history of consuming unpasteurized dairy products, and more than half (57.2%) had been exposed to livestock in the past year. The most common clinical symptoms were weakness and fatigue (66.7%), joint pain (62.7%), and fever (73.1%), while back pain (65.7%) and knee pain (48.3%) were the dominant musculoskeletal symptoms. In addition, arthritis (24.4%), spondylitis (15.4%), and sacroiliitis (13.4%) were the primary identified musculoskeletal complications. Conclusion: The clinical manifestations of brucellosis include common symptoms, such as fever, weakness, fatigue, and joint pain, which were more prevalent in male patients. In addition, musculoskeletal complications are prominent features of the disease. According to bone scan and MRI results, approximately 20% of hospitalized brucellosis patients had bone-joint complications, including arthritis, spondylitis, and sacroiliitis.http://sjh.umsha.ac.ir/article-1-3086-en.pdfbrucellosisbone complicationsdiagnosis
spellingShingle Peyman Eini
Narmin Karimian
Azar Pirdehghan
Pooya Eini
Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
پزشکی بالینی ابن سینا
brucellosis
bone complications
diagnosis
title Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
title_full Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
title_fullStr Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
title_full_unstemmed Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
title_short Bone and Joint Complications in Hospitalized Brucellosis Patients: A 10-Year Study in Hamadan, Iran
title_sort bone and joint complications in hospitalized brucellosis patients a 10 year study in hamadan iran
topic brucellosis
bone complications
diagnosis
url http://sjh.umsha.ac.ir/article-1-3086-en.pdf
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AT narminkarimian boneandjointcomplicationsinhospitalizedbrucellosispatientsa10yearstudyinhamadaniran
AT azarpirdehghan boneandjointcomplicationsinhospitalizedbrucellosispatientsa10yearstudyinhamadaniran
AT pooyaeini boneandjointcomplicationsinhospitalizedbrucellosispatientsa10yearstudyinhamadaniran