Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction

Aflatoxin B1 impairs the growth and development of chicken PGCs through oxidative stress and mitochondrial dysfunction

Aflatoxins harm the reproductive system and gamete development in animals. Primordial germ cells (PGCs) in chickens, as ancestral cells of gametes, are essential for genetic transmission, yet the impact and mechanisms of aflatoxins on them remain elusive. This study systematically investigated the e...

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Bibliographic Details
Main Authors: Ying-Jie Niu, Jun Wu, Wenjie Ren, Guangzheng Liu, Gaoyuan Wu, Yixiu Peng, Dan Zheng, Kai Jin, Qisheng Zuo, Guohui Li, Wei Han, Xiang-Shun Cui, Guohong Chen, Bichun Li
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Aflatoxin B1
Primordial germ cells
Oxidative stress
Mitochondrion
NRF2
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651325000636
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