Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus.

Association of a rapidly selected 4.3kb transposon-containing structural variation with a P450-based resistance to pyrethroids in the African malaria vector Anopheles funestus.

Deciphering the evolutionary forces controlling insecticide resistance in malaria vectors remains a prerequisite to designing molecular tools to detect and assess resistance impact on control tools. Here, we demonstrate that a 4.3kb transposon-containing structural variation is associated with pyret...

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Main Authors: Leon M J Mugenzi, Theofelix A Tekoh, Stevia T Ntadoun, Achille D Chi, Mahamat Gadji, Benjamin D Menze, Magellan Tchouakui, Helen Irving, Murielle J Wondji, Gareth D Weedall, Jack Hearn, Charles S Wondji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-07-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1011344
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