Endogenous Fe2+‐triggered self‐targeting nanomicelles for self‐amplifying intracellular oxidative stress
Abstract Background Artesunate (ASA) acts as an •O₂− source through the breakdown of endoperoxide bridges catalyzed by Fe2+, yet its efficacy in ASA‐based nanodrugs is limited by poor intracellular delivery. Methods ASA–hyaluronic acid (HA) conjugates were formed from hydrophobic ASA and hydrophilic...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-02-01
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| Series: | Animal Models and Experimental Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ame2.12468 |
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