Causal relationship between mitochondrial proteins and risks of aortic aneurysms and aortic dissection: a Mendelian randomization study

Causal relationship between mitochondrial proteins and risks of aortic aneurysms and aortic dissection: a Mendelian randomization study

Abstract Background Mitochondrial dysfunction may be linked to the development of aortic aneurysm (AA) and aortic dissection (AD). This study aimed to evaluate the potential associations between proteins related to mitochondrial function and the risks of AA/AD using Mendelian randomization (MR). Met...

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Bibliographic Details
Main Authors: Lei Wang, Yuzuo Lin, Ziyan Lin, Qingtong Wu, Guodong Zhong, Liangwan Chen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Journal of Cardiothoracic Surgery
Subjects:
Mitochondria
Aortic aneurysm
Aortic dissection
Mendelian randomization
Online Access:https://doi.org/10.1186/s13019-025-03389-8
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