Regulation of disease signaling by YOD1: potential implications for therapeutic strategies

Regulation of disease signaling by YOD1: potential implications for therapeutic strategies

Abstract YOD1 (OTUD2) is a pivotal deubiquitinating enzyme (DUB) of the Otubain family. It plays an essential role in protein degradation and the regulation of cell signal transduction, influencing various biological processes. The activity of YOD1 is mediated through its three structural domains: t...

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Bibliographic Details
Main Authors: Jiawei Zhao, Xiaotong Guo, Houzhong Li, Yujing Chen, Jingjing Du, Juzheng Zhang, Jinfeng Gan, Peitao Wu, Siqi Chen, Xinwen Zhang, Jinfeng Yang, Jiamin Jin
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
Deubiquitinases
YOD1
Signaling pathways
Disease
Inhibitor
Online Access:https://doi.org/10.1186/s12935-025-03881-0
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