The role of TNF-α inhibitor in glioma virotherapy: A mathematical model

Virotherapy, using herpes simplex virus, represents a promising therapy of glioma. But the innate immune response, which includes TNF-α produced by macrophages, reduces the effectiveness of the treatment. Hence treatment with TNF-α inhibitor may increase the effectiveness of the virotherapy. In the...

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Bibliographic Details
Main Authors: Elzbieta Ratajczyk, Urszula Ledzewicz, Maciej Leszczynski, Avner Friedman
Format: Article
Language:English
Published: AIMS Press 2016-12-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2017020
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