The role of TNF-α inhibitor in glioma virotherapy: A mathematical model
Virotherapy, using herpes simplex virus, represents a promising therapy of glioma. But the innate immune response, which includes TNF-α produced by macrophages, reduces the effectiveness of the treatment. Hence treatment with TNF-α inhibitor may increase the effectiveness of the virotherapy. In the...
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Main Authors: | Elzbieta Ratajczyk, Urszula Ledzewicz, Maciej Leszczynski, Avner Friedman |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2016-12-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2017020 |
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