Mutators can drive the evolution of multi-resistance to antibiotics.
Antibiotic combination therapies are an approach used to counter the evolution of resistance; their purported benefit is they can stop the successive emergence of independent resistance mutations in the same genome. Here, we show that bacterial populations with 'mutators', organisms with d...
Saved in:
| Main Authors: | Danna R Gifford, Ernesto Berríos-Caro, Christine Joerres, Marc Suñé, Jessica H Forsyth, Anish Bhattacharyya, Tobias Galla, Christopher G Knight |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2023-06-01
|
| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010791&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Epigenetic modifications and metabolic gene mutations drive resistance evolution in response to stimulatory antibiotics
by: Hui Lin, et al.
Published: (2025-01-01) -
Isolated cell behavior drives the evolution of antibiotic resistance
by: Tatiana Artemova, et al.
Published: (2015-07-01) -
Where antibiotic resistance mutations meet quorum-sensing
by: Rok Krašovec, et al.
Published: (2014-06-01) -
Mutational spectrum drives the rise of mutator bacteria.
by: Alejandro Couce, et al.
Published: (2013-01-01) -
Anaerobiosis and Mutations Can Reduce Susceptibility of <i>Pseudomonas aeruginosa</i> to Tobramycin Without Reducing the Cellular Concentration of the Antibiotic
by: Woravimol Krittaphol, et al.
Published: (2025-02-01)