Building of CuO<sub>2</sub>@Cu-TA@DSF/DHA Nanoparticle Targets MAPK Pathway to Achieve Synergetic Chemotherapy and Chemodynamic for Pancreatic Cancer Cells

Building of CuO<sub>2</sub>@Cu-TA@DSF/DHA Nanoparticle Targets MAPK Pathway to Achieve Synergetic Chemotherapy and Chemodynamic for Pancreatic Cancer Cells

<b>Background/Objectives:</b> With the increase of reactive oxygen species (ROS) production, cancer cells can avoid cell death and damage by up-regulating antioxidant programs. Therefore, it will be more effective to induce cell death by using targeted strategies to further improve ROS l...

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Bibliographic Details
Main Authors: Jiaru Zhang, Zuoping Li, Zhenzhen Xie, Shiwan You, Yanbing Chen, Yuling Zhang, Jing Zhang, Na Zhao, Xiling Deng, Shiguo Sun
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Pharmaceutics
Subjects:
dihydroartemisinin
disulfiram
chemotherapy
chemodynamic
synergetic therapy
Online Access:https://www.mdpi.com/1999-4923/16/12/1614
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