An overview of ivabradine

This article provides an overview of the therapeutic effects of ivabradine in the treatment of coronary artery disease (CAD), and in the management of stable angina pectoris (SAP) and congestive cardiac failure (CCF). Patients with SAP have a reduced quality of life and are unable to work efficientl...

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Main Authors: Tumelo Ramoleta, Natalie Schellack, Elmien Bronkhorst
Format: Article
Language:English
Published: AOSIS 2016-12-01
Series:South African Family Practice
Subjects:
Online Access:https://safpj.co.za/index.php/safpj/article/view/4572
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author Tumelo Ramoleta
Natalie Schellack
Elmien Bronkhorst
author_facet Tumelo Ramoleta
Natalie Schellack
Elmien Bronkhorst
author_sort Tumelo Ramoleta
collection DOAJ
description This article provides an overview of the therapeutic effects of ivabradine in the treatment of coronary artery disease (CAD), and in the management of stable angina pectoris (SAP) and congestive cardiac failure (CCF). Patients with SAP have a reduced quality of life and are unable to work efficiently, resulting in the increased use of healthcare resources. Unlike the other antianginal drugs (i.e. the beta-blockers, calcium-channel blockers and organic nitrates), ivabradine specifically targets the If current of the sinus node. It reduces the frequency of angina attacks and increases the time until symptoms during work appear. Clinical evidence has shown that ivabradine is an effective anti-ischaemic and antianginal agent, comparable to the beta-blockers and calcium-channel antagonist in controlling the symptoms of myocardial ischemia.
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institution Kabale University
issn 2078-6190
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language English
publishDate 2016-12-01
publisher AOSIS
record_format Article
series South African Family Practice
spelling doaj-art-61805357e7084c87b3b9155e9a53336a2025-08-20T03:47:09ZengAOSISSouth African Family Practice2078-61902078-62042016-12-01586363910.4102/safp.v58i6.45723668An overview of ivabradineTumelo Ramoleta0Natalie Schellack1Elmien Bronkhorst2Sefako Makgatho Health Sciences UniversitySefako Makgatho Health Sciences UniversitySefako Makgatho Health Sciences UniversityThis article provides an overview of the therapeutic effects of ivabradine in the treatment of coronary artery disease (CAD), and in the management of stable angina pectoris (SAP) and congestive cardiac failure (CCF). Patients with SAP have a reduced quality of life and are unable to work efficiently, resulting in the increased use of healthcare resources. Unlike the other antianginal drugs (i.e. the beta-blockers, calcium-channel blockers and organic nitrates), ivabradine specifically targets the If current of the sinus node. It reduces the frequency of angina attacks and increases the time until symptoms during work appear. Clinical evidence has shown that ivabradine is an effective anti-ischaemic and antianginal agent, comparable to the beta-blockers and calcium-channel antagonist in controlling the symptoms of myocardial ischemia.https://safpj.co.za/index.php/safpj/article/view/4572ivabradineif currentsinus nodecongestive cardiac failureangina pectorisantianginal agent
spellingShingle Tumelo Ramoleta
Natalie Schellack
Elmien Bronkhorst
An overview of ivabradine
South African Family Practice
ivabradine
if current
sinus node
congestive cardiac failure
angina pectoris
antianginal agent
title An overview of ivabradine
title_full An overview of ivabradine
title_fullStr An overview of ivabradine
title_full_unstemmed An overview of ivabradine
title_short An overview of ivabradine
title_sort overview of ivabradine
topic ivabradine
if current
sinus node
congestive cardiac failure
angina pectoris
antianginal agent
url https://safpj.co.za/index.php/safpj/article/view/4572
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AT natalieschellack anoverviewofivabradine
AT elmienbronkhorst anoverviewofivabradine
AT tumeloramoleta overviewofivabradine
AT natalieschellack overviewofivabradine
AT elmienbronkhorst overviewofivabradine