Diverse functions of NLRP3 inflammasome in PANoptosis and diseases

Abstract NOD-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) is a vital sensor of the innate immune system, capable of responding to various exogenous invading pathogens and endogenous cell injury. Once the danger signal is detected, NLRP3 recruits downstream molecules to assemble into...

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Bibliographic Details
Main Authors: Yuanyuan Jiang, Zhiyuan Qiang, Yue Liu, Liwei Zhu, Long Xiao, Zhenfang Du, Rong Cai, Sheng Qiang
Format: Article
Language:English
Published: Nature Publishing Group 2025-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02689-1
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