Iodine supplementation for pregnancy in Portugal: identification of nutritional composition of iodine containing supplements and characterization of pharmacy dispenses from 2008-2022

BackgroundIodine is essential for the proper development of the central nervous system. In Portugal, despite of self-reports of iodine supplements intake by pregnant women, iodine deficiency still prevails. This study intended to characterize the pharmacy sales of iodine-containing supplements and t...

Full description

Saved in:
Bibliographic Details
Main Authors: Sarai Isabel Machado, Susana Roque, Maria Lopes-Pereira, Maria José Costeira, Patrício Costa, Nuno Borges, Ruben Pereira, Zilda Mendes, António Teixeira Rodrigues, Joana Almeida Palha
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1582610/full
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:BackgroundIodine is essential for the proper development of the central nervous system. In Portugal, despite of self-reports of iodine supplements intake by pregnant women, iodine deficiency still prevails. This study intended to characterize the pharmacy sales of iodine-containing supplements and their use by women in Portugal.MethodsData from all available supplements with indication for use in the prenatal time, for the period 2008-2022, was obtained from the Portuguese Association of Pharmacies. To infer from the use of iodine supplements by women during preconception, pregnancy and lactation, pharmacy dispenses, between 2019 and 2021, were collected from a sample of female consumers, identified with at least one prescription of iodine-containing supplements.ResultsEighty-eight per cent of the iodine-containing supplements state the recommended iodine concentration. The annual sales increased continuously, reaching an estimated of 109 µg per day in 2022. Estimated mean duration of supplementation to women prescribed with iodine-containing supplements for preconception/pregnancy/lactation was of 4.5 months (SD = 3.8) and less than 1% of women was covered for the advisable period of 18 months.ConclusionThe estimated duration of iodine supplementation to women during preconception, pregnancy and lactation is below recommendations. Additional public health measures, such as universal salt iodization and literacy campaigns are needed to ensure iodine sufficiency to women and their developing fetus.
ISSN:1664-2392