The importance of human FcgammaRI in mediating protection to malaria.
The success of passive immunization suggests that antibody-based therapies will be effective at controlling malaria. We describe the development of fully human antibodies specific for Plasmodium falciparum by antibody repertoire cloning from phage display libraries generated from immune Gambian adul...
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| Main Authors: | Richard S McIntosh, Jianguo Shi, Richard M Jennings, Jonathan C Chappel, Tania F de Koning-Ward, Tim Smith, Judith Green, Marjolein van Egmond, Jeanette H W Leusen, Maria Lazarou, Jan van de Winkel, Tarran S Jones, Brendan S Crabb, Anthony A Holder, Richard J Pleass |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2007-05-01
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| Series: | PLoS Pathogens |
| Online Access: | https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.0030072&type=printable |
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