Exploring the use of physical rehabilitation for sepsis survivors: a scoping review

Objectives To explore the use, parameters, safety and outcomes of physical rehabilitation for adults with sepsis.Design We conducted a scoping review following the Joanna Briggs Institute framework.Participants Studies were eligible for inclusion in the study if they included: (1) adults 18 and olde...

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Main Authors: Michelle E Kho, Bram Rochwerg, Jenna Smith-Turchyn, Christopher Farley, Jordon L Hvizd, Anastasia N L Newman, Heather O’Grady, Sophia Werdens Abram, Neeraja Nannapaneni, Shannon McKenney
Format: Article
Language:English
Published: BMJ Publishing Group 2025-07-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/7/e097125.full
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author Michelle E Kho
Bram Rochwerg
Jenna Smith-Turchyn
Christopher Farley
Jordon L Hvizd
Anastasia N L Newman
Heather O’Grady
Sophia Werdens Abram
Neeraja Nannapaneni
Shannon McKenney
author_facet Michelle E Kho
Bram Rochwerg
Jenna Smith-Turchyn
Christopher Farley
Jordon L Hvizd
Anastasia N L Newman
Heather O’Grady
Sophia Werdens Abram
Neeraja Nannapaneni
Shannon McKenney
author_sort Michelle E Kho
collection DOAJ
description Objectives To explore the use, parameters, safety and outcomes of physical rehabilitation for adults with sepsis.Design We conducted a scoping review following the Joanna Briggs Institute framework.Participants Studies were eligible for inclusion in the study if they included: (1) adults 18 and older, (2) with a previous diagnosis of sepsis, (3) using a physical rehabilitation intervention at any point of sepsis management, (4) published in English or French.Procedure We searched seven databases and screened titles and abstracts, reviewed full texts and performed data extraction independently and in duplicate. We summarised findings narratively using the “population, context, concept” framework and used descriptive statistics where appropriate. End-users reviewed and commented on study findings.Results We included 58 studies, representing 77 434 participants, with the majority (79%) being published in the last decade. A large proportion (36%) of physical rehabilitation interventions included exercise and were overseen by a physical therapist (41%). The parameters of the interventions varied widely. However, all interventions (100%) were hospital based and the interventions implemented appeared safe. Of the 28 studies evaluating effectiveness of the intervention, function improved in most studies (78%) following physical rehabilitation.Conclusion Research addressing physical rehabilitation for patients with sepsis is increasing. Physical rehabilitation appears safe and may improve functional outcomes in those with sepsis. Future research should report details of intervention parameters and evaluate rehabilitation post-hospital discharge to maximise impact on function and quality of life for sepsis survivors.Registration The protocol was registered on Open Science Framework Registries (Registration DOI: https://doi.org/10.17605/OSF.IO/2EPJ6).
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spelling doaj-art-61644780adb64d9f9d1fd5315d617f992025-08-20T03:32:22ZengBMJ Publishing GroupBMJ Open2044-60552025-07-0115710.1136/bmjopen-2024-097125Exploring the use of physical rehabilitation for sepsis survivors: a scoping reviewMichelle E Kho0Bram Rochwerg1Jenna Smith-Turchyn2Christopher Farley3Jordon L Hvizd4Anastasia N L Newman5Heather O’Grady6Sophia Werdens Abram7Neeraja Nannapaneni8Shannon McKenney9School of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaMedicine (Critical Care), McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaSchool of Rehabilitation Science, McMaster University, Hamilton, Ontario, CanadaMcMaster University, Hamilton, Ontario, CanadaObjectives To explore the use, parameters, safety and outcomes of physical rehabilitation for adults with sepsis.Design We conducted a scoping review following the Joanna Briggs Institute framework.Participants Studies were eligible for inclusion in the study if they included: (1) adults 18 and older, (2) with a previous diagnosis of sepsis, (3) using a physical rehabilitation intervention at any point of sepsis management, (4) published in English or French.Procedure We searched seven databases and screened titles and abstracts, reviewed full texts and performed data extraction independently and in duplicate. We summarised findings narratively using the “population, context, concept” framework and used descriptive statistics where appropriate. End-users reviewed and commented on study findings.Results We included 58 studies, representing 77 434 participants, with the majority (79%) being published in the last decade. A large proportion (36%) of physical rehabilitation interventions included exercise and were overseen by a physical therapist (41%). The parameters of the interventions varied widely. However, all interventions (100%) were hospital based and the interventions implemented appeared safe. Of the 28 studies evaluating effectiveness of the intervention, function improved in most studies (78%) following physical rehabilitation.Conclusion Research addressing physical rehabilitation for patients with sepsis is increasing. Physical rehabilitation appears safe and may improve functional outcomes in those with sepsis. Future research should report details of intervention parameters and evaluate rehabilitation post-hospital discharge to maximise impact on function and quality of life for sepsis survivors.Registration The protocol was registered on Open Science Framework Registries (Registration DOI: https://doi.org/10.17605/OSF.IO/2EPJ6).https://bmjopen.bmj.com/content/15/7/e097125.full
spellingShingle Michelle E Kho
Bram Rochwerg
Jenna Smith-Turchyn
Christopher Farley
Jordon L Hvizd
Anastasia N L Newman
Heather O’Grady
Sophia Werdens Abram
Neeraja Nannapaneni
Shannon McKenney
Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
BMJ Open
title Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
title_full Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
title_fullStr Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
title_full_unstemmed Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
title_short Exploring the use of physical rehabilitation for sepsis survivors: a scoping review
title_sort exploring the use of physical rehabilitation for sepsis survivors a scoping review
url https://bmjopen.bmj.com/content/15/7/e097125.full
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