Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules

Delineation of single-cell Altas provides new insights for development of coronary artery lesions in Kawasaki disease: bad and good signaling molecules

BackgroundKawasaki Disease (KD) is a vasculitis syndrome featured with a high and persistent fever in children. It is the leading cause of coronary artery lesions (CALs) for children in developed countries.MethodsSingle-cell RNA sequencing analyses were performed for the peripheral blood mononuclear...

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Bibliographic Details
Main Authors: Qiuping Lin, Xin Lv, Qingzhu Qiu, Lianni Mei, Liqin Chen, Sirui Song, Wei Liu, Xunwei Jiang, Min Huang, Libing Shen, Tingting Xiao, Lijian Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pediatrics
Subjects:
Kawasaki disease
coronary artery lesion
CD14 monocyte
signaling molecule
MCH-II
resistin
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1596643/full
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