A novel Tc17 population recruited by tumor cells promotes tumor progression in gastric cancer

A novel Tc17 population recruited by tumor cells promotes tumor progression in gastric cancer

ObjectiveThe tumor microenvironment (TME) plays a crucial role in tumor progression. Recent advancements in single-cell sequencing technology have identified Tc17 cells, a newfound subset of CD8+ T cells with a phenotype similar to Th17, within the gastric cancer (GC) microenvironment. However, the...

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Bibliographic Details
Main Authors: Yichao Wang, Hao Yuan, Yayun Tan, Li Wu, Xinchen Zhao, Zeyuan Yang, Shaoxing Dai, Naixue Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
tumor microenvironment
single-cell RNA-seq
Tc17 cells
CXCL16
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1592328/full
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