Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents

Enterocolic lymphocytic phlebitis is phlebitis of unknown etiology in which lymphocytes affect veins without arteries and shows evidence of systemic vasculitis in the intestinal wall and mesentery, mainly in the small intestine and colon. Although patients present with a variety of gastrointestinal...

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Main Authors: Soh Okano, Takashi Yao, Osamu Nomura, Akihito Nagahara, Toshiaki Hagiwara, Kiichi Sugimoto, Makoto Takahashi, Kazuhiro Sakamoto
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2022/5120607
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author Soh Okano
Takashi Yao
Osamu Nomura
Akihito Nagahara
Toshiaki Hagiwara
Kiichi Sugimoto
Makoto Takahashi
Kazuhiro Sakamoto
author_facet Soh Okano
Takashi Yao
Osamu Nomura
Akihito Nagahara
Toshiaki Hagiwara
Kiichi Sugimoto
Makoto Takahashi
Kazuhiro Sakamoto
author_sort Soh Okano
collection DOAJ
description Enterocolic lymphocytic phlebitis is phlebitis of unknown etiology in which lymphocytes affect veins without arteries and shows evidence of systemic vasculitis in the intestinal wall and mesentery, mainly in the small intestine and colon. Although patients present with a variety of gastrointestinal symptoms and findings like those of inflammatory bowel disease or ischemic bowel disease, there are no specific findings for enterocolic lymphocytic phlebitis. As a result, a diagnosis tends to be made after surgery. There are few case reports of enterocolic lymphocytic phlebitis, and the impact of chronic courses and immunosuppressive drugs on enterocolic lymphocytic phlebitis is not well known. A 47-year-old man was treated with infliximab and steroids for unexplained ulceration and narrowing of the ileocecal area, which was suspected to be inflammatory bowel disease with atypical findings. Lymphocytic phlebitis was noted in the surgical specimen, and enterocolic lymphocytic phlebitis was diagnosed. No recurrence of enterocolic lymphocytic phlebitis was observed postoperatively. This disease should also be considered among patients with inflammatory bowel disease-like lesions that do not respond to infliximab or steroids.
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institution Kabale University
issn 2090-679X
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publishDate 2022-01-01
publisher Wiley
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series Case Reports in Pathology
spelling doaj-art-613df2323190401a8b17e1baf01234732025-02-03T06:10:54ZengWileyCase Reports in Pathology2090-679X2022-01-01202210.1155/2022/5120607Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive AgentsSoh Okano0Takashi Yao1Osamu Nomura2Akihito Nagahara3Toshiaki Hagiwara4Kiichi Sugimoto5Makoto Takahashi6Kazuhiro Sakamoto7Department of Human PathologyDepartment of Human PathologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of Coloproctological SurgeryDepartment of Coloproctological SurgeryDepartment of Coloproctological SurgeryDepartment of Coloproctological SurgeryEnterocolic lymphocytic phlebitis is phlebitis of unknown etiology in which lymphocytes affect veins without arteries and shows evidence of systemic vasculitis in the intestinal wall and mesentery, mainly in the small intestine and colon. Although patients present with a variety of gastrointestinal symptoms and findings like those of inflammatory bowel disease or ischemic bowel disease, there are no specific findings for enterocolic lymphocytic phlebitis. As a result, a diagnosis tends to be made after surgery. There are few case reports of enterocolic lymphocytic phlebitis, and the impact of chronic courses and immunosuppressive drugs on enterocolic lymphocytic phlebitis is not well known. A 47-year-old man was treated with infliximab and steroids for unexplained ulceration and narrowing of the ileocecal area, which was suspected to be inflammatory bowel disease with atypical findings. Lymphocytic phlebitis was noted in the surgical specimen, and enterocolic lymphocytic phlebitis was diagnosed. No recurrence of enterocolic lymphocytic phlebitis was observed postoperatively. This disease should also be considered among patients with inflammatory bowel disease-like lesions that do not respond to infliximab or steroids.http://dx.doi.org/10.1155/2022/5120607
spellingShingle Soh Okano
Takashi Yao
Osamu Nomura
Akihito Nagahara
Toshiaki Hagiwara
Kiichi Sugimoto
Makoto Takahashi
Kazuhiro Sakamoto
Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
Case Reports in Pathology
title Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
title_full Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
title_fullStr Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
title_full_unstemmed Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
title_short Enterocolic Lymphocytic Phlebitis Treated Preoperatively with Biologics and Immunosuppressive Agents
title_sort enterocolic lymphocytic phlebitis treated preoperatively with biologics and immunosuppressive agents
url http://dx.doi.org/10.1155/2022/5120607
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