Protective Effects of Pasireotide in LPS-Induced Acute Lung Injury

Protective Effects of Pasireotide in LPS-Induced Acute Lung Injury

<b>Background/Objectives:</b> Acute lung injury (ALI) is an inflammatory condition characterized by tissue barrier damage, which leads to vascular leakage, pulmonary edema, and compromised gas exchange. Lipopolysaccharides (LPS) are a component of Gram-negative bacteria, which trigger in...

Full description

Saved in:

Bibliographic Details
Main Authors:	Saikat Fakir, Md Matiur Rahman Sarker, Madan Sigdel, Nektarios Barabutis
Format:	Article
Language:	English
Published:	MDPI AG 2025-06-01
Series:	Pharmaceuticals
Subjects:	Somatostatin inflammation homeostasis sepsis growth hormone
Online Access:	https://www.mdpi.com/1424-8247/18/7/942
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Corrigendum: Estrogens modulate somatostatin receptors expression and synergize with the somatostatin analog pasireotide in prostate cells
by: Valentina Rossi, et al.
Published: (2024-12-01)

Structural insights into the binding modes of lanreotide and pasireotide with somatostatin receptor 1
by: Zicheng Zeng, et al.
Published: (2025-05-01)

Real-Life Data on the Safety of Pasireotide in Acromegaly: Insights from EudraVigilance
by: Ioana Rada Popa Ilie, et al.
Published: (2024-12-01)

Somatostatin Mitigates Gastric Mucosal Damage Induced by LPS in a Male Wistar Rat Model of Sepsis
by: Sergio D. Paredes, et al.
Published: (2025-03-01)

Somatostatin does not attenuate intestinal injury in dextran sodium sulphate-induced subacute colitis
by: J. D. van Bergeijk, et al.
Published: (1998-01-01)

Predictors of therapeutic failure in GH and prolactin co-secreting pituitary adenomas
by: Marta Araujo-Castro, et al.
Published: (2025-07-01)

Molecular identification of somatostatin family in tilapia and the effect of food intake on pss2 and sstr3a
by: Ran Cai, et al.
Published: (2025-04-01)

The Anti-Inflammatory Potential of Levosimendan in Sepsis: An Experimental Study Using a LPS-Induced Rat Model
by: Elif Dedeler Ertanıdır, et al.
Published: (2025-06-01)

The effects of oleuropein on lung and heart injury in cecal ligation and puncture - induced sepsis
by: Hüseyin Serkan Erol, et al.
Published: (2020-10-01)

Age-dependent patterns of somatostatinergic neurons in sympathetic paravertebral ganglia
by: A. I. Emanuilov, et al.
Published: (2023-10-01)

The Role of Somatostatin in the Gastrointestinal Tract
by: Konstantinos Papantoniou, et al.
Published: (2025-05-01)

SOMATOSTATIN RECEPTORS AS POTENTIALTHERAPEUTIC TARGETS IN THE TREATMENT OF ADVANCED ADRENOCORTICAL CANCER. A CASE REPORT
by: A. A. Kolomeytseva, et al.
Published: (2018-05-01)

THERAPY WITH SOMATOSTATIN ANALOGUES IN PATIENTS WITH CASTRATION-REFRACTORY PROSTATE CANCER
by: K. Y. Kanukoev, et al.
Published: (2015-04-01)

Long-Term Results of Cabergoline Add-on Long-Acting Somatostatin Analogue Therapy in Acromegaly Patients
by: Mehmet Muhittin Yalçın, et al.
Published: (2024-10-01)

Comparative characteristics of risk factors as predictors of coronary heart disease in women during an epidemiological and clinical examination
by: F. N. Kasumova, et al.
Published: (2019-03-01)

HORMONAL HOMEOSTASIS IN FEMALE CORONARY HEART DISEASE PATIENTS FROM DIFFERENT AGE GROUPS
by: F. N. Kasumova
Published: (2012-10-01)

Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells
by: Xiaobo Zhang, et al.
Published: (2025-05-01)

Efficacy and predictors of response to somatostatin analogues in patients with ectopic ACTH syndrome
by: Olga O. Golounina, et al.
Published: (2024-12-01)

Primary pancreatic lymphoma camouflaged under the umbrella of spectrum of neuroendocrine tumors in somatostatin receptor imaging
by: Nikita Sampathirao, et al.
Published: (2020-07-01)

Insulinoma with suspected mutant somatostatin receptor expression according to histological examination
by: Shunichiro Onish, et al.
Published: (2024-11-01)

Dwarfing of fruit trees: from old cognitions to new insights
by: Lele Chu, et al.
Published: (2025-03-01)

Mesenchymal stem cells protect against sepsis-associated acute kidney injury by inducing Gal-9/Tim-3 to remodel immune homeostasis
by: Congjuan Luo, et al.
Published: (2023-12-01)

Study on the Mechanism of UMI-77 in the Treatment of Sepsis-Induced Acute Lung Injury Based on Transcriptomics and Metabolomics
by: Zhang J, et al.
Published: (2024-12-01)

Amantadine reduces sepsis-induced brain injury via NLRP3/caspase-1 inflammasome activation
by: Pinar Karabacak, et al.
Published: (2025-05-01)

Sparstolonin B nano-formulation attenuates LPS-induced lung injury
by: Qinghe Meng, et al.
Published: (2025-04-01)

Serum LINC01278 serves as a negative biomarker for sepsis and its up-regulation inhibits LPS-induced inflammatory response in THP-1 cells
by: Ying Gu, et al.
Published: (2025-07-01)

Morphofunctional characteristic of gastric adipocytes in patients with type 2 diabetes mellitus
by: Ashot Musaelovich Mkrtumyan, et al.
Published: (2009-06-01)

Insight into the Potential of Somatostatin Vaccination with Goats as a Model: From a Perspective of the Gastrointestinal Microbiota
by: Xiaoli Zhang, et al.
Published: (2025-03-01)

Role of the endothelial cell glycocalyx in sepsis-induced acute kidney injury
by: Yixun Wang, et al.
Published: (2025-04-01)

5-deoxy-rutaecarpine protects against LPS-induced acute lung injury via inhibiting NLRP3 inflammasome-related inflammation
by: Jinque Luo, et al.
Published: (2025-01-01)

LL-37 Attenuates Sepsis-Induced Lung Injury by Alleviating Inflammatory Response and Epithelial Cell Oxidative Injury via ZBP1-Mediated Autophagy
by: Hu Gao, et al.
Published: (2025-06-01)

Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential
by: Kaiying Lv, et al.
Published: (2025-01-01)

Effects of Cholinergic and Opioid Antagonists on In Vitro Release of Met-Enkephalin, Somatostatin and Insulin-like Growth Factor-1 by and PENK Expression in Crop, Proventriculus and Duodenum of Newly Hatched Chickens
by: Colin G. Scanes, et al.
Published: (2025-06-01)

Effect of β-casein A2 cow milk supplementation on physical growth, inflammation, growth-related hormones, and nutritional biomarkers in stunted children
by: Revi Gama Hatta Novika, et al.
Published: (2025-06-01)

Reduced sensitivity to thyroid hormones is associated with differentiated thyroid cancer in the euthyroid thyroidectomy population
by: Huaijin Xu, et al.
Published: (2025-06-01)

LncRNA AP001007 protects human renal tubular epithelial HK-2 cells and kidney organoids from LPS-induced injury
by: Sheng Lin, et al.
Published: (2024-11-01)

The dual role of neutrophils in sepsis-associated liver injury
by: Lexin Fang, et al.
Published: (2025-02-01)

Octreotide in the treatment of neuroendocrine carcinomas: Is the success achieved?
by: L. Yu. Morgunov
Published: (2015-06-01)

Dexmedetomidine reduces acute lung injury caused by LPS through the SIRT3 signaling pathway in vivo
by: Jian Chen, et al.
Published: (2025-06-01)

Corticosteroids in sports-related injuries: Friend or Foe
by: A. Rotunno, et al.
Published: (2016-12-01)